Introduction The association between the checkpoint kinase 2* 1100delC (CHEK2*
1100delC) and breast cancer has been extensively explored. Objective In light of the recent …

Over the past 20 years, high-penetrance pathogenic mutations in genes BRCA1, BRCA2,
TP53, PTEN, STK11 and CDH1 and moderate-penetrance mutations in genes CHEK2, ATM …

Purpose Breast cancer is considered as the most frequent female malignancy. Altered gene
expressions due to genetic polymorphisms in the BRCA1, BRCA2, RAD51, and HER2 …

Background About 3885 women are diagnosed with breast cancer and 1285 die from the
disease each year in Bulgaria. However no genetic testing to identify the mutations in high …

Background: To date several common mutations in BRCA1 and BRCA2 associated with
breast cancer have been reported in different populations. However, the common BRCA1 …

Background: The incidence of breast cancer in India is on the rise and is rapidly becoming
the number one cancer in females, pushing the cervical cancer to the second position. Most …

The present review attempts to etch the distribution pattern of BRCA1 and BRCA2 gene
mutations along with variation in their mutational spectrum thus portraying the phenotypic …

Objective: Worldwide, breast cancer is the most common malignancy among women. In
Turkey, breast cancer is also the most common cancer among women with the frequency of …

Background Breast cancer is characterized by various malignant tumors arise from breast
tissues, age, genetic factors, diet and environmental factors, reproductive and hormonal …

Address: 1 Professor, Department of Medical Microbiology, College of Medicine, University
of Al-Qadisiyah, Diwaniyah, Iraq, Email: hammadi. abttan@ qu. edu. iq, 2 Assist Professor …