Abstract Purpose Adverse drug reactions (ADRs) represent a common and potentially
preventable cause of unplanned hospitalization, increasing morbidity, mortality, and …

Purpose Potentially inappropriate medication (PIM) use causes preventable adverse drug
reactions in older patients. Several assessment tools have been published to identify and …

Inappropriate polypharmacy, especially in older people, imposes a substantial burden of
adverse drug events, ill health, disability, hospitalization, and even death. The single most …

The complexity and heterogeneity of patients with multimorbidity and polypharmacy renders
traditional disease‐oriented guidelines often inadequate and complicates clinical decision …

Background The term potentially inadequate medication (PIM) is used to describe
substances that may be unsuitable for use in the elderly and should be avoided. The …

Background Inappropriate polypharmacy is a particular concern in older people and is
associated with negative health outcomes. Choosing the best interventions to improve …

Globally, the number of drug prescriptions is increasing causing more adverse drug events,
which is now a significant cause of mortality, morbidity, and disability that has reached …

Objective to validate STOPPFrail, a list of explicit criteria for potentially inappropriate
medication (PIM) use in frail older adults with limited life expectancy. Design a Delphi …

Only two years after publishing the first edition of this handbook, we started working on a
second edition. Three reasons were responsible for why we thought that a second edition …

Polypharmacy characterizes ongoing prescription of multiple medications in a patient.
Following the demographic change and growing number of elderly patients, polypharmacy …