Gene expression–based prognostic signatures in lung cancer: ready for clinical use?
J Subramanian, R Simon - Journal of the National Cancer …, 2010 - academic.oup.com
A substantial number of studies have reported the development of gene expression–based
prognostic signatures for lung cancer. The ultimate aim of such studies should be the …
prognostic signatures for lung cancer. The ultimate aim of such studies should be the …
Prognostic immune markers in non–small cell lung cancer
Tumor-associated immune responses have polarized effects in regulating tumor growth.
Although a clear association has been shown between the tumor immune response and …
Although a clear association has been shown between the tumor immune response and …
ibex: An open infrastructure software platform to facilitate collaborative work in radiomics
Purpose: Radiomics, which is the high‐throughput extraction and analysis of quantitative
image features, has been shown to have considerable potential to quantify the tumor …
image features, has been shown to have considerable potential to quantify the tumor …
A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies
JR Kratz, J He, SK Van Den Eeden, ZH Zhu, W Gao… - The Lancet, 2012 - thelancet.com
Background The frequent recurrence of early-stage non-small-cell lung cancer (NSCLC) is
generally attributable to metastatic disease undetected at complete resection. Management …
generally attributable to metastatic disease undetected at complete resection. Management …
[HTML][HTML] The International Association for the Study of Lung Cancer Staging Project: prognostic factors and pathologic TNM stage in surgically managed non-small cell …
K Chansky, JP Sculier, JJ Crowley, D Giroux… - Journal of thoracic …, 2009 - Elsevier
Purpose: To assess the impact of cell type, age, and gender in addition to pathologic tumor,
node, metastasis (TNM) stage in surgically managed stage I-IIIA non-small cell lung cancer …
node, metastasis (TNM) stage in surgically managed stage I-IIIA non-small cell lung cancer …
Prognostic value and reproducibility of pretreatment CT texture features in stage III non-small cell lung cancer
Purpose To determine whether pretreatment CT texture features can improve patient risk
stratification beyond conventional prognostic factors (CPFs) in stage III non-small cell lung …
stratification beyond conventional prognostic factors (CPFs) in stage III non-small cell lung …
Folic acid-modified dendrimer-entrapped gold nanoparticles as nanoprobes for targeted CT imaging of human lung adencarcinoma
H Wang, L Zheng, C Peng, M Shen, X Shi, G Zhang - Biomaterials, 2013 - Elsevier
We report a new usage of folic acid-modified dendrimer-entrapped gold nanoparticles (Au
DENPs-FA) as nanoprobes for in vitro and in vivo targeted computed tomography (CT) …
DENPs-FA) as nanoprobes for in vitro and in vivo targeted computed tomography (CT) …
A clonal expression biomarker associates with lung cancer mortality
An aim of molecular biomarkers is to stratify patients with cancer into disease subtypes
predictive of outcome, improving diagnostic precision beyond clinical descriptors such as …
predictive of outcome, improving diagnostic precision beyond clinical descriptors such as …
Wnt3a: functions and implications in cancer
Wnt3a, one of Wnt family members, plays key roles in regulating pleiotropic cellular
functions, including self-renewal, proliferation, differentiation, and motility. Accumulating …
functions, including self-renewal, proliferation, differentiation, and motility. Accumulating …
Prognostic and predictive value of a malignancy-risk gene signature in early-stage non–small cell lung cancer
DT Chen, YL Hsu, WJ Fulp, D Coppola… - Journal of the …, 2011 - academic.oup.com
Background The malignancy-risk gene signature is composed of numerous proliferative
genes and has been applied to predict breast cancer risk. We hypothesized that the …
genes and has been applied to predict breast cancer risk. We hypothesized that the …