Lipid metabolism and lipophagy in cancer
The tumor microenvironment can be hypoxic, acidic, and deficient in nutrients, thus causing
the metabolism of tumor cells as well as the neighboring stromal cells to be remodelled to …
the metabolism of tumor cells as well as the neighboring stromal cells to be remodelled to …
[HTML][HTML] Function, detection and alteration of acylcarnitine metabolism in hepatocellular carcinoma
S Li, D Gao, Y Jiang - Metabolites, 2019 - mdpi.com
Acylcarnitines play an essential role in regulating the balance of intracellular sugar and lipid
metabolism. They serve as carriers to transport activated long-chain fatty acids into …
metabolism. They serve as carriers to transport activated long-chain fatty acids into …
[HTML][HTML] Specific gut microbiome and serum metabolome changes in lung cancer patients
F Zhao, R An, L Wang, J Shan, X Wang - Frontiers in cellular and …, 2021 - frontiersin.org
Background Lung cancer (LC) is one of the most aggressive, prevalent and fatal
malignancies. Gut microbes and their associated metabolites are thought to cause and …
malignancies. Gut microbes and their associated metabolites are thought to cause and …
Role of Nrf2 in cell senescence regulation
H Yuan, Y Xu, Y Luo, NX Wang, JH Xiao - Molecular and Cellular …, 2021 - Springer
Nuclear factor-E2-related factor 2 (Nrf2) is a key transcription factor known to be involved in
maintaining cell redox balance and signal transduction and plays central role in reducing …
maintaining cell redox balance and signal transduction and plays central role in reducing …
[HTML][HTML] Mass spectrometry imaging-based metabolomics to visualize the spatially resolved reprogramming of carnitine metabolism in breast cancer
C Sun, F Wang, Y Zhang, J Yu, X Wang - Theranostics, 2020 - ncbi.nlm.nih.gov
New insights into tumor-associated metabolic reprogramming have provided novel
vulnerabilities that can be targeted for cancer therapy. Here, we propose a mass …
vulnerabilities that can be targeted for cancer therapy. Here, we propose a mass …
[HTML][HTML] Acyl-CoA-binding protein drives glioblastoma tumorigenesis by sustaining fatty acid oxidation
C Duman, K Yaqubi, A Hoffmann, AA Acikgöz… - Cell Metabolism, 2019 - cell.com
Glioblastoma multiforme (GBM) undergoes metabolic reprogramming to meet the high ATP
and anabolic demands of the tumor cells. However, the role of fatty acid oxidation (FAO) and …
and anabolic demands of the tumor cells. However, the role of fatty acid oxidation (FAO) and …
[HTML][HTML] Fatty acid metabolism in aggressive B-cell lymphoma is inhibited by tetraspanin CD37
R Peeters, J Cuenca-Escalona, EA Zaal… - Nature …, 2022 - nature.com
The importance of fatty acid (FA) metabolism in cancer is well-established, yet the
mechanisms underlying metabolic reprogramming remain elusive. Here, we identify …
mechanisms underlying metabolic reprogramming remain elusive. Here, we identify …
[HTML][HTML] The role and therapeutic implication of CPTs in fatty acid oxidation and cancers progression
J Wang, H Xiang, Y Lu, T Wu, G Ji - American Journal of Cancer …, 2021 - ncbi.nlm.nih.gov
Cancer cells must maintain metabolic homeostasis under a wide range of conditions and
meet their own energy needs in order to survive and reproduce. In addition to glycolysis …
meet their own energy needs in order to survive and reproduce. In addition to glycolysis …
[HTML][HTML] The role of lipid metabolism in tumor immune microenvironment and potential therapeutic strategies
D Wang, Q Ye, H Gu, Z Chen - Frontiers in Oncology, 2022 - frontiersin.org
Aberrant lipid metabolism is nonnegligible for tumor cells to adapt to the tumor
microenvironment (TME). It plays a significant role in the amount and function of immune …
microenvironment (TME). It plays a significant role in the amount and function of immune …
[HTML][HTML] Lipid and glucose metabolism in senescence
B Liu, Q Meng, X Gao, H Sun, Z Xu, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Senescence is an inevitable biological process. Disturbances in glucose and lipid
metabolism are essential features of cellular senescence. Given the important roles of these …
metabolism are essential features of cellular senescence. Given the important roles of these …