Systematic review: impact of resveratrol exposure during pregnancy on maternal and fetal outcomes in animal models of human pregnancy complications—are we …
JRT Darby, MHBM Dollah, TRH Regnault… - Pharmacological …, 2019 - Elsevier
Resveratrol (RSV) has been reported to have potential beneficial effects in the complicated
pregnancy. Various pregnancy complications lead to a suboptimal in utero environment that …
pregnancy. Various pregnancy complications lead to a suboptimal in utero environment that …
Reduced neurosteroid exposure following preterm birth and its' contribution to neurological impairment: a novel avenue for preventative therapies
Children born preterm are at an increased risk of developing cognitive problems and neuro-
behavioral disorders such as attention deficit hyperactivity disorder (ADHD) and anxiety …
behavioral disorders such as attention deficit hyperactivity disorder (ADHD) and anxiety …
Effects of prenatal stress on behavioural and neurodevelopmental outcomes are altered by maternal separation in the neonatal period
GK Crombie, HK Palliser, JC Shaw… - …, 2021 - Elsevier
Background Chronic psychosocial stress during pregnancy and/or after birth, and the
associated elevation in cortisol, is linked with the onset of behavioural disorders in …
associated elevation in cortisol, is linked with the onset of behavioural disorders in …
Prenatal hypoxia impairs cardiac mitochondrial and ventricular function in guinea pig offspring in a sex-related manner
LP Thompson, L Chen, BM Polster… - American Journal of …, 2018 - journals.physiology.org
Adverse intrauterine conditions cause fetal growth restriction and increase the risk of adult
cardiovascular disease. We hypothesize that intrauterine hypoxia impairs fetal heart …
cardiovascular disease. We hypothesize that intrauterine hypoxia impairs fetal heart …
Prenatal stress induces translational disruption associated with myelination deficits
GK Crombie, HK Palliser, JC Shaw, BA Hanley… - Dev. Neurosci, 2023 - karger.com
Disruptions to neurodevelopment are known to be linked to behavioral disorders in
childhood and into adulthood. The fetal brain is extremely vulnerable to stimuli that alter …
childhood and into adulthood. The fetal brain is extremely vulnerable to stimuli that alter …
Neurosteroid replacement therapy using the allopregnanolone-analogue ganaxolone following preterm birth in male guinea pigs
Background Children born preterm, especially boys, are at increased risk of developing
attention deficit hyperactivity disorder (ADHD) and learning difficulties. We propose that …
attention deficit hyperactivity disorder (ADHD) and learning difficulties. We propose that …
Evaluating changes in GABAergic and glutamatergic pathways in early life following prenatal stress and postnatal neurosteroid supplementation
GK Crombie, HK Palliser, JC Shaw… - …, 2022 - Elsevier
Background A correct balance of activity of the GABA and glutamate systems is vital for
optimal neurodevelopment and general CNS function, and the dysregulation of this balance …
optimal neurodevelopment and general CNS function, and the dysregulation of this balance …
Hepatic cytochrome P450 function is reduced by life-long Western diet consumption in guinea pig independent of birth weight
Introduction Non-alcoholic fatty liver disease (NAFLD) is characterised by accumulation of
triglycerides and cholesterol within the liver and dysregulation of specific hepatic …
triglycerides and cholesterol within the liver and dysregulation of specific hepatic …
Adult vascular dysfunction in foetal growth‐restricted guinea‐pigs is associated with a neonate‐adult switching in Nos3 DNA methylation
Aim Foetal growth restriction (FGR) is associated with endothelial dysfunction and
cardiovascular diseases in adult subjects. Early vascular remodelling and epigenetic …
cardiovascular diseases in adult subjects. Early vascular remodelling and epigenetic …
[PDF][PDF] This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and …
DRP D FRASER, MR Heider, R Swennen… - researchgate.net
Roots, tubers and bananas (RTB) are vital staples for food security in the worlds' poorest
nations. A major constraint to current RTB breeding programmes is limited knowledge about …
nations. A major constraint to current RTB breeding programmes is limited knowledge about …