[HTML][HTML] DPP4 and ACE2 in diabetes and COVID-19: therapeutic targets for cardiovascular complications?
I Valencia, C Peiró, Ó Lorenzo… - Frontiers in …, 2020 - frontiersin.org
COVID-19 outbreak, caused by severe acute respiratory syndrome (SARS)-CoV-2
coronavirus has become an urgent health and economic challenge. Diabetes is a risk factor …
coronavirus has become an urgent health and economic challenge. Diabetes is a risk factor …
Emerging role of dipeptidyl peptidase-4 in autoimmune disease
J Huang, X Liu, Y Wei, X Li, S Gao, L Dong… - Frontiers in …, 2022 - frontiersin.org
Dipeptidyl-peptidase IV (DPP4), originally identified as an aminopeptidase in 1960s, is an
ubiquitously expressed protease presented as either a membrane-bound or soluble form …
ubiquitously expressed protease presented as either a membrane-bound or soluble form …
[PDF][PDF] The MERS-CoV receptor DPP4 as a candidate binding target of the SARS-CoV-2 spike
Y Li, Z Zhang, L Yang, X Lian, Y Xie, S Li, S Xin, P Cao… - Iscience, 2020 - cell.com
The ongoing outbreak of the novel coronavirus pneumonia COVID-19 has caused great
number of cases and deaths, but our understanding about the pathogen SARS-CoV-2 …
number of cases and deaths, but our understanding about the pathogen SARS-CoV-2 …
Anti‐inflammatory Effects of Empagliflozin and Gemigliptin on LPS‐Stimulated Macrophage via the IKK/NF‐κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways
N Lee, YJ Heo, SE Choi, JY Jeon… - Journal of …, 2021 - Wiley Online Library
Background. Sodium‐glucose cotransporter 2 (SGLT2) and dipeptidyl peptidase‐4 (DPP‐4)
inhibitors are glucose‐lowering drugs whose anti‐inflammatory properties have recently …
inhibitors are glucose‐lowering drugs whose anti‐inflammatory properties have recently …
The roles of dipeptidyl peptidase 4 (DPP4) and DPP4 inhibitors in different lung diseases: new evidence
T Zhang, X Tong, S Zhang, D Wang, L Wang… - Frontiers in …, 2021 - frontiersin.org
CD26/Dipeptidyl peptidase 4 (DPP4) is a type II transmembrane glycoprotein that is widely
expressed in various organs and cells. It can also exist in body fluids in a soluble form …
expressed in various organs and cells. It can also exist in body fluids in a soluble form …
Anti-inflammatory properties of antidiabetic drugs: a “promised land” in the COVID-19 era?
N Katsiki, E Ferrannini - Journal of Diabetes and its Complications, 2020 - Elsevier
Inflammation is implicated in the development and severity of the coronavirus disease 2019
(COVID-19), as well as in the pathophysiology of diabetes. Diabetes, especially when …
(COVID-19), as well as in the pathophysiology of diabetes. Diabetes, especially when …
[HTML][HTML] SARS-CoV-2 infection of phagocytic immune cells and COVID-19 pathology: Antibody-dependent as well as independent cell entry
O Matveeva, Y Nechipurenko, D Lagutkin… - Frontiers in …, 2022 - frontiersin.org
Our review summarizes the evidence that COVID-19 can be complicated by SARS-CoV-2
infection of immune cells. This evidence is widespread and accumulating at an increasing …
infection of immune cells. This evidence is widespread and accumulating at an increasing …
[HTML][HTML] Milk protein digestion and the gut microbiome influence gastrointestinal discomfort after cow milk consumption in healthy subjects
S Tagliamonte, RB Lumaga, F De Filippis… - Food Research …, 2023 - Elsevier
Many healthy people suffer from milk-related gastrointestinal discomfort (GID) despite not
being lactose intolerant; the mechanisms underpinning such condition are unknown. This …
being lactose intolerant; the mechanisms underpinning such condition are unknown. This …
Disentangling conflicting evidence on DPP-4 inhibitors and outcomes of COVID-19: narrative review and meta-analysis
BM Bonora, A Avogaro, GP Fadini - Journal of Endocrinological …, 2021 - Springer
Background The infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has rapidly spread all over the world, becoming pandemic. Several studies have shown …
2) has rapidly spread all over the world, becoming pandemic. Several studies have shown …
Obesity and COVID-19: mechanistic insights from adipose tissue
L Yu, X Zhang, S Ye, H Lian, H Wang… - The Journal of Clinical …, 2022 - academic.oup.com
Obesity is associated with an increase in morbidity and mortality from coronavirus disease
2019 (COVID-19). The risk is related to the cytokine storm, a major contributor to multiorgan …
2019 (COVID-19). The risk is related to the cytokine storm, a major contributor to multiorgan …