Background Organophosphate (OP) pesticides have been associated with a decline in
semen quality, although there are still considerable arguments about the magnitude of the …

Male reproductive functions, which include testicular steroidogenesis, spermatogenesis, and
sexual/erectile functions are key in male fertility, but may be adversely altered by several …

Background The continuous use of pesticides, such as dichlorvos, is a common agricultural
and domestic practice. However, it is associated with shortfalls like testicular toxicity through …

Background Tamoxifen (TAM) is a widely used drug in patients with gynecomastia and
breast cancer. TAM exerts its anticancer effects via its antiestrogenic activities. Unfortunately …

Background Although highly active antiretroviral therapy (HAART) is effective in the
management of HIV, it has been reported to induce hepatic injury and non-alcoholic fatty …

Introduction Bisphenol F (BPF), an alternative to bisphenol A has been implicated as a
gonadotoxic substance. BPF has been shown to induce hormonal imbalance and testicular …

Aim This study evaluated the effect of lead, with or without zinc co-administration, on
steroidogenic and xanthine oxidase (XO)/uric acid (UA)/caspase 3-mediated apoptotic …

Background: Activation of caspase 3 has been implicated in the pathogenesis of I/R injury in
various organs, but there is a paucity of data on its role in IIRI. Also, no reports were found …

This study investigated the effect of BPF on male sexual performance and the quality of the
offspring. Eighty (80) Male Wistar rats (n= 10 per group) were randomised into normal saline …

Introduction Bisphenol F (BPF) has been shown to disrupt testicular functions via
perturbation of testicular redox balance, while omega-3 fatty acid (O3FA) has been …