In mammals, sperm fertilization potential relies on efficient progression within the female
genital tract to reach and fertilize the oocyte. This fundamental property is supported by the …

Androgen receptor signaling pathway is necessary to complete spermatogenesis in testes.
Difference between androgen binding location in Sertoli cell classifies androgen receptor …

Pakistan is third largest country in term of goat population with distinct characteristics of
breeds and estimated population of 78.2 million. Punjab province has 37% of country's total …

STUDY QUESTIONS Are extracellular vesicles (EVs) in the murine oviduct (oviductosomes,
OVS) conserved in humans and do they play a role in the fertility of Pmca4−/− females …

Infertility is a significant global health problem that currently affects one of six couples in
reproductive age. The quality of male reproductive cells dramatically decreased over the last …

As a second messenger in cellular signal transduction, calcium signaling extensively
participates in various physiological activities, including spermatogenesis and the regulation …

Purpose Nitric oxide (NO) is a free radical synthesized mainly by nitric oxide synthases
(NOSs). NO regulates many aspects in sperm physiology in different species. However, in …

Abstract Plasma membrane Ca 2+ transport ATPases (PMCA1-4, ATP2B1-4) are
responsible for removing excess Ca 2+ from the cell in order to keep the cytosolic Ca 2+ ion …

Diabetic nephropathy (DN) is a highly complex syndrome involving multiple dysregulated
biological processes. Long non‑coding RNAs (lncRNAs) are now believed to have an …

Nitric oxide (NO) is a signaling molecule responsible for initiation of molecular events that
influence sperm functionality in a concentration-dependent manner. It is still not fully …