Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

Traditionally, the presence and severity of obstructive sleep apnea (OSA) have been defined
by the apnea–hypopnea index (AHI). Continuous positive airway pressure is generally first …

Rationale: Therapies for obstructive sleep apnea (OSA) could be administered on the basis
of a patient's own phenotypic causes (“traits”) if a clinically applicable approach were …

Rationale: Approximately one-third of patients with obstructive sleep apnea (OSA) treated
with hypoglossal nerve stimulation (HGNS) therapy are incomplete responders, despite …

Obstructive sleep apnea (OSA) syndrome is a multi-factorial disorder. Recently identified
pathophysiological contributing factors include airway collapsibility, poor pharyngeal muscle …

A possible precision-medicine approach to treating obstructive sleep apnoea (OSA) involves
targeting ventilatory instability (elevated loop gain) using supplemental inspired oxygen in …

Abstract Study Objectives Obstructive sleep apnea (OSA) is characterized by multiple
“endotypic traits,” including pharyngeal collapsibility, muscle compensation, loop gain, and …

Recent advances in obstructive sleep apnoea (OSA) pathophysiology and translational
research have opened new lines of investigation for OSA treatment and management. Key …

Rationale: Mandibular advancement device (MAD) treatment efficacy varies among patients
with obstructive sleep apnea. Objectives: The current study aims to explain underlying …

Overnight pulse oximetry allows the relatively non‐invasive estimation of peripheral blood
haemoglobin oxygen saturations (SpO2), and forms part of the typical polysomnogram …