Since their first discovery in the 1960s by Alec Bangham, liposomes have been shown to be
effective drug delivery systems for treating various cancers. Several liposome-based …

Liposomes hold great potential as gene and drug delivery vehicles due to their
biocompatibility and modular properties, coupled with the major advantage of attenuating …

The ability to efficiently access cytosolic proteins is desired in both biological research and
medicine. However, targeting intracellular proteins is often challenging, because to reach …

Biotherapy has recently become a hotspot research topic with encouraging prospects in
various fields due to a wide range of treatments applications, as demonstrated in preclinical …

This Review illustrates the evaluation of permeability of lipid membranes from molecular
dynamics (MD) simulation primarily using water and oxygen as examples. Membrane …

Lipid nanoparticles (LNPs) are currently the most clinically advanced nonviral carriers for the
delivery of small interfering RNA (siRNA). Free siRNA molecules suffer from unfavorable …

Philip L. Yeagle Page 1 Biochimica et BiophysicaActa 822 (1985) 267-287 267 Elsevier
BBA85280 Cholesterol and the cell membrane Philip L. Yeagle Department of Biochemistry …

Opinions of the usefulness of liposomes in various biotechnological applications range from
unsubstantiated optimism to undeserved pessimism. This article reviews the background …

The discovery of liposome or lipid vesicle emerged from self forming enclosed lipid bi-layer
upon hydration; liposome drug delivery systems have played a significant role in formulation …

Spontaneous solute and solvent permeation through membranes is of vital importance to
human life, be it gas exchange in red blood cells, metabolite excretion, drug/toxin uptake, or …