Emerging systems biology approaches in nanotoxicology: Towards a mechanism-based understanding of nanomaterial hazard and risk

PM Costa, B Fadeel - Toxicology and applied pharmacology, 2016 - Elsevier
Engineered nanomaterials are being developed for a variety of technological applications.
However, the increasing use of nanomaterials in society has led to concerns about their …

Exposure to nanopolystyrene and its 4 chemically modified derivatives at predicted environmental concentrations causes differently regulatory mechanisms in …

M Qu, H Chen, H Lai, X Liu, D Wang, X Zhang - Chemosphere, 2022 - Elsevier
Nanoplastics represented by nanopolystyrene (NPS) and its chemically modified derivatives
are environmentally ecotoxicological hotpots in recent years, but their toxicity and underlying …

Does size matter? A proteomics-informed comparison of the effects of polystyrene beads of different sizes on macrophages

V Collin-Faure, B Dalzon, J Devcic, H Diemer… - Environmental …, 2022 - pubs.rsc.org
Plastics are one of the most preoccupying emerging pollutants. Macroplastics released into
the environment degrade into microplastics and nanoplastics. Because of their small size …

Chronic training induces metabolic and proteomic response in male and female basketball players: salivary modifications during in-season training programs

S Luti, R Militello, G Pinto, A Illiano, A Amoresano… - Healthcare, 2023 - mdpi.com
The aim of this study was to characterize the salivary proteome and metabolome of highly
trained female and male young basketball players, highlighting common and different traits …

Characterization and therapeutic effect of a pH stimuli responsive polymeric nanoformulation for controlled drug release

MV Cano-Cortes, JA Laz-Ruiz, JJ Diaz-Mochon… - Polymers, 2020 - mdpi.com
Despite the large number of polymeric nanodelivery systems that have been recently
developed, there is still room for improvement in terms of therapeutic efficiency. Most …

Selective anticancer therapy based on a HA-CD44 interaction inhibitor loaded on polymeric nanoparticles

JM Espejo-Román, B Rubio-Ruiz, V Cano-Cortés… - Pharmaceutics, 2022 - mdpi.com
Hyaluronic acid (HA), through its interactions with the cluster of differentiation 44 (CD44),
acts as a potent modulator of the tumor microenvironment, creating a wide range of …

Modulation of plasma proteomic profile by regular training in male and female basketball players: a preliminary study

R Militello, G Pinto, A Illiano, S Luti, F Magherini… - Frontiers in …, 2022 - frontiersin.org
Monitoring fatigue and recovery during training periods contributes to identifying the best
training methods to achieve sports performance. To date, little is known about sex-related …

Time-resolved proteomic visualization of dendrimer cellular entry and trafficking

L Wang, L Yang, L Pan, NR Kadasala… - Journal of the …, 2015 - ACS Publications
Our understanding of the complex cell entry pathways would greatly benefit from a
comprehensive characterization of key proteins involved in this dynamic process. Here we …

An effective polymeric nanocarrier that allows for active targeting and selective drug delivery in cell coculture systems

MV Cano-Cortes, P Altea-Manzano, JA Laz-Ruiz… - Nanoscale, 2021 - pubs.rsc.org
In this manuscript, we report the development of a versatile, robust, and stable targeting
nanocarrier for active delivery. This nanocarrier is based on bifunctionalized polymeric …

Development and Evaluation of Smart Polymeric and Lipidic Nanoparticles for Theranosis of Breast and Pancreatic Cancer

SA Navarro Marchal - 2022 - digibug.ugr.es
Nanomedicine is playing a growing part in pharmaceutical research and development,
primarily in the form of nanoparticle-based delivery systems for drugs and imaging agents …