Fluorescence quenching methods are useful to obtain information about the conformational
and/or dynamic changes of proteins in complex macromolecular systems. In this review …

Inhibition of Angiotensin Converting Enzyme (ACE) is identified as a main therapeutic target
in controlling hypertension. The principal intent of this work is to investigate the ACE …

Combinatorial inhibition of Topoisomerase 1 (TOP1) and Poly (ADP-ribose) polymerase 1
(PARP1) is an attractive therapeutic strategy which is under active investigation to address …

Gold nanoparticles of different sizes have been synthesized using sodium citrate as a
reducing agent for tetrachloroauric (III) acid. The formed gold nanoparticles have been …

The solvatochromic behavior of two newly synthesized naphthalimide derivatives (I and II)
which have potential antioxidative activities in anticarcinogenic drug development treatment …

The pharmacological importance, particularly the anti-cancer and chemopreventive
potentials, of organochalcogen compounds has attracted wide research attention recently …

In this study, a hypochlorite detector has been synthesized and evaluated by fluorescent and
UV–Vis method. Among the analytes, only ClO− could weaken the fluorescence intensity …

This article describes the prime role of selenium (Se) and its compounds in mammalian
biochemical systems, performing diverse functions like maintenance of health through …

A new spectrofluorimetric method for measuring finasteride (FIN) in tablet dosage form was
developed. The method was based on FIN quenching the intrinsic fluorescence of bovine …

Fragment-based in silico screening against dynamin I (dynI) GTPase activity identified the 1,
8-naphthalimide framework as a potential scaffold for the design of new inhibitors targeting …