Evolution of the experimental models of cholangiocarcinoma

A Massa, C Varamo, F Vita, S Tavolari, C Peraldo-Neia… - Cancers, 2020 - mdpi.com
Cholangiocarcinoma (CCA) is a rare, aggressive disease with poor overall survival. In
advanced cases, surgery is often not possible or fails; in addition, there is a lack of effective …

Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance

DF Calvisi, L Boulter, J Vaquero… - Nature Reviews …, 2023 - nature.com
Cholangiocarcinoma (CCA) is a rare malignancy that develops at any point along the biliary
tree. CCA has a poor prognosis, its clinical management remains challenging, and effective …

N-glycosylation profiling of colorectal cancer cell lines reveals association of fucosylation with differentiation and caudal type homebox 1 (CDX1)/Villin mRNA …

S Holst, AJM Deuss, GW Van Pelt, SJ Van Vliet… - Molecular & Cellular …, 2016 - ASBMB
Various cancers such as colorectal cancer (CRC) are associated with alterations in protein
glycosylation. CRC cell lines are frequently used to study these (glyco) biological changes …

Comprehensive characterization of the effects of ellagic acid and urolithins on colorectal cancer and key‐associated molecular hallmarks: MicroRNA cell specific …

A González‐Sarrías… - Molecular Nutrition & …, 2016 - Wiley Online Library
Scope Ellagitannins, ellagic acid, and the colonic metabolites urolithins (Uros) exhibit
anticancer effects against colon cells, but a comprehensive molecular analysis has not been …

Medical 3D printing with polyjet technology: effect of material type and printing orientation on printability, surface structure and cytotoxicity

KH Schneider, G Oberoi, E Unger, K Janjic… - 3D Printing in …, 2023 - Springer
Due to its high printing resolution and ability to print multiple materials simultaneously, inkjet
technology has found wide application in medicine. However, the biological safety of 3D …

Diminished Ovarian Reserve in Endometriosis: Insights from In Vitro, In Vivo, and Human Studies—A Systematic Review

Z Tan, X Gong, CC Wang, T Zhang… - International Journal of …, 2023 - mdpi.com
Endometriosis, a prevalent disorder in women of reproductive age, is often associated with
undesired infertility. Ovarian reserve, an essential measure of ovarian function that is crucial …

Unraveling the key role of chromatin structure in cancer development through epigenetic landscape characterization of oral cancer

Y Xue, L Liu, Y Zhang, Y He, J Wang, Z Ma, T Li… - Molecular Cancer, 2024 - Springer
Epigenetic alterations, such as those in chromatin structure and DNA methylation, have
been extensively studied in a number of tumor types. But oral cancer, particularly oral …

Rapid and efficient testing of the toxicity of graphene-related materials in primary human lung cells

J Frontiñan-Rubio, VJ González, E Vázquez… - Scientific Reports, 2022 - nature.com
Graphene and its derivative materials are manufactured by numerous companies and
research laboratories, during which processes they can come into contact with their …

Chemokine 25–induced signaling suppresses colon cancer invasion and metastasis

HJ Chen, R Edwards, S Tucci, P Bu… - The Journal of …, 2012 - Am Soc Clin Investig
Chemotactic cytokines (chemokines) can help regulate tumor cell invasion and metastasis.
Here, we show that chemokine 25 (CCL25) and its cognate receptor chemokine receptor 9 …

[HTML][HTML] Redox modulation of oxidatively-induced DNA damage by ascorbate enhances both in vitro and ex-vivo DNA damage formation and cell death in melanoma …

HA Najeeb, T Sanusi, G Saldanha, K Brown… - Free Radical Biology …, 2024 - Elsevier
Elevated genomic instability in cancer cells suggests a possible model-scenario for their
selective killing via the therapeutic delivery of well-defined levels of further DNA damage. To …