A tale of two viruses: immunological insights into HCV/HIV coinfection
ST Gobran, P Ancuta, NH Shoukry - Frontiers in immunology, 2021 - frontiersin.org
Nearly 2.3 million individuals worldwide are coinfected with human immunodeficiency virus
(HIV) and hepatitis C virus (HCV). Odds of HCV infection are six times higher in people living …
(HIV) and hepatitis C virus (HCV). Odds of HCV infection are six times higher in people living …
Virological Mechanisms in the Coinfection between HIV and HCV
MC Liberto, E Zicca, G Pavia, A Quirino… - Mediators of …, 2015 - Wiley Online Library
Due to shared transmission routes, coinfection with Hepatitis C Virus (HCV) is common in
patients infected by Human Immunodeficiency Virus (HIV). The immunepathogenesis of …
patients infected by Human Immunodeficiency Virus (HIV). The immunepathogenesis of …
HCV coinfection contributes to HIV pathogenesis by increasing immune exhaustion in CD8 T-cells
N Rallón, M García, J García-Samaniego… - PLoS …, 2017 - journals.plos.org
Background There are several contributors to HIV-pathogenesis or insufficient control of the
infection. However, whether HIV/HCV-coinfected population exhibits worst evolution of HIV …
infection. However, whether HIV/HCV-coinfected population exhibits worst evolution of HIV …
Do the epidemiology, physiological mechanisms and characteristics of hepatocellular carcinoma in HIV-infected patients justify specific screening policies?
M Gelu-Simeon, R Sobesky, S Haïm-Boukobza… - Aids, 2014 - journals.lww.com
Reducing the incidence of hepatocellular carcinoma (HCC) in HIV-infected patients has
become a serious problem when managing these patients. There are many explanations for …
become a serious problem when managing these patients. There are many explanations for …
Links between human LINE-1 retrotransposons and hepatitis virus-related hepatocellular carcinoma
T Honda - Frontiers in chemistry, 2016 - frontiersin.org
Hepatocellular carcinoma (HCC) accounts for approximately 80% of liver cancers, the third
most frequent cause of cancer mortality. The most prevalent risk factors for HCC are …
most frequent cause of cancer mortality. The most prevalent risk factors for HCC are …
[HTML][HTML] Hepatitis C virus core protein enhances HIV-1 replication in human macrophages through TLR2, JNK, and MEK1/2-dependent upregulation of TNF-α and IL-6
G Swaminathan, D Pascual, G Rival, R Perales-Linares… - FEBS letters, 2014 - Elsevier
Despite their differential cell tropisms, HIV-1 and HCV dramatically influence disease
progression in coinfected patients. Macrophages are important target cells of HIV-1. We …
progression in coinfected patients. Macrophages are important target cells of HIV-1. We …
HIV-reservoir size is not affected either by HCV coinfection or by direct acting antivirals (DAAs) therapy
B Álvarez, MA Navarrete-Muñoz, V Briz… - Scientific Reports, 2022 - nature.com
The role of HCV on the HIV reservoir is controversial since the reduction on HIV-DNA levels
after HCV eradication with IFNα/RBV treatment seems to be the result of drugs instead of …
after HCV eradication with IFNα/RBV treatment seems to be the result of drugs instead of …
[HTML][HTML] The Era of DAAs: Assessing the Patients' Characteristics, Clinical Impact, and Emergence of Comorbidities in HIV/HCV-Coinfected versus HIV-Infected …
B Álvarez-Álvarez, L Prieto-Pérez… - Journal of Clinical …, 2024 - mdpi.com
Objective: To determine whether HIV-infected individuals versus individuals with HIV/HCV
coinfection, in the era of interferon-free therapies, exhibit an increased incidence of …
coinfection, in the era of interferon-free therapies, exhibit an increased incidence of …
Immunogenetic studies of the hepatitis C virus infection in an era of pan-genotype antiviral therapies-Effective treatment is coming
JH Ellwanger, V de Lima Kaminski… - Infection, Genetics and …, 2018 - Elsevier
What are the factors that influence human hepatitis C virus (HCV) infection, hepatitis status
establishment, and disease progression? Firstly, one has to consider the genetic …
establishment, and disease progression? Firstly, one has to consider the genetic …
Immuno-pathomechanism of liver fibrosis: targeting chemokine CCL2-mediated HIV: HCV nexus
AWW Ansari, RE Schmidt, EM Shankar… - Journal of translational …, 2014 - Springer
Even in the era of successful combination antiretroviral therapy (cART), co-infection of
Hepatitis C virus (HCV) remains one of the leading causes of non-AIDS-related mortality and …
Hepatitis C virus (HCV) remains one of the leading causes of non-AIDS-related mortality and …