Dendrimers are well-defined, highly branched, multivalent and monodisperse molecules
which host a range of attractive, yet functional, chemical and biological characteristics. A …

Peptide-based subunit vaccines utilise minimal immunogenic components (ie peptides) to
generate highly specific immune responses, without triggering adverse reactions. However …

Group A Streptococcus (GAS) infection can cause a variety of diseases in humans, ranging
from common sore throats and skin infections, to more invasive diseases and life …

Peptide antigens have been widely used in the development of vaccines, especially for
those against autoimmunity-inducing pathogens and cancers. However, peptide-based …

Group A Streptococcus (GAS) and GAS-related infections are a worldwide challenge, with
no commercial GAS vaccine available. Polyethylenimine (PEI) attaches to the cells' surface …

Co‐assembling vaccines composed of a lipidated HER2‐derived antigenic CH401 peptide
and either a lipophilic adjuvant, Pam3CSK4, α‐GalCer, or lipid A 506, were evaluated as …

Liposomes, which are artificial phospholipid vesicles with a bilayer membrane structure,
have been developed and evaluated as a promising delivery system for vaccines. Here, we …

Rapid advancements in the field of anticancer vaccination paved the way for recognizing
several targets to stimulate an immune response against one or multiple tumor-associated …

The design of subunit vaccines requires new adjuvant systems. We designed and
synthesized new lipopeptides (cysteine-based) of low molecular weight with different …