Imaging challenges in biomaterials and tissue engineering

AA Appel, MA Anastasio, JC Larson, EM Brey - Biomaterials, 2013 - Elsevier
Biomaterials are employed in the fields of tissue engineering and regenerative medicine
(TERM) in order to enhance the regeneration or replacement of tissue function and/or …

X-ray microtomography in biology

R Mizutani, Y Suzuki - Micron, 2012 - Elsevier
Progress in high-resolution X-ray microtomography has provided us with a practical
approach to determining three-dimensional (3D) structures of opaque samples at …

Endothelial progenitor cells and mesenchymal stem cells seeded onto β-TCP granules enhance early vascularization and bone healing in a critical-sized bone defect …

C Seebach, D Henrich, C Kähling… - … Engineering Part A, 2010 - liebertpub.com
Question/aim: Lack of vessels indicates an insufficient nutritional supply of a bone graft and
may limit the recruitment of bone-forming cells. Our aim was to evaluate the influence of …

Micro-CT–a digital 3D microstructural voyage into scaffolds: a systematic review of the reported methods and results

IF Cengiz, JM Oliveira, RL Reis - Biomaterials research, 2018 - spj.science.org
Background Cell behavior is the key to tissue regeneration. Given the fact that most of the
cells used in tissue engineering are anchorage-dependent, their behavior including …

A mechanobiological model for tissue differentiation that includes angiogenesis: a lattice-based modeling approach

S Checa, PJ Prendergast - Annals of biomedical engineering, 2009 - Springer
Mechanobiological models have previously been used to predict the time course of the
tissue differentiation process, with the local mechanical environment as the regulator of cell …

The effect of multi-material architecture on the ex vivo osteochondral integration of bioprinted constructs

ML Bedell, Z Wang, KJ Hogan, AL Torres, HA Pearce… - Acta biomaterialia, 2023 - Elsevier
Extrusion bioprinted constructs for osteochondral tissue engineering were fabricated to
study the effect of multi-material architecture on encapsulated human mesenchymal stem …

Engineering in-vitro stem cell-based vascularized bone models for drug screening and predictive toxicology

A Pirosa, R Gottardi, PG Alexander… - Stem cell research & …, 2018 - Springer
The production of veritable in-vitro models of bone tissue is essential to understand the
biology of bone and its surrounding environment, to analyze the pathogenesis of bone …

Three-dimensional printing for craniofacial bone tissue engineering

C Shen, L Witek, RL Flores, N Tovar… - … Engineering Part A, 2020 - liebertpub.com
The basic concepts from the fields of biology and engineering are integrated into tissue
engineering to develop constructs for the repair of damaged and/or absent tissues …

BMP2 genetically engineered MSCs and EPCs promote vascularized bone regeneration in rat critical-sized calvarial bone defects

X He, R Dziak, X Yuan, K Mao, R Genco, M Swihart… - PloS one, 2013 - journals.plos.org
Current clinical therapies for critical-sized bone defects (CSBDs) remain far from ideal.
Previous studies have demonstrated that engineering bone tissue using mesenchymal stem …

From material to tissue: Biomaterial development, scaffold fabrication, and tissue engineering

JD Kretlow, AG Mikos - AIChE Journal, 2008 - Wiley Online Library
The need for techniques to facilitate the regeneration of failing or destroyed tissues remains
great with the aging of the worldwide population and the continued incidence of trauma and …