Asthma is one of the most common respiratory disease that affects both children and adults
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …

For a long time, scientists have tried to describe disorders just by genetic or environmental
factors. However, the role of epigenetics in human diseases has been considered from a …

We examined common variation in asthma risk by conducting a meta-analysis of worldwide
asthma genome-wide association studies (23,948 asthma cases, 118,538 controls) of …

Genome‐wide association studies (GWAS) can identify common alleles that contribute to
complex disease susceptibility. Despite the large number of SNPs assessed in each study …

Asthma and allergy are common conditions with complex etiologies involving both genetic
and environmental contributions. Recent genome‐wide association studies (GWAS) and …

Asthma is a common disease with a complex risk architecture including both genetic and
environmental factors. We performed a meta-analysis of North American genome-wide …

Women have higher prevalence of asthma compared with men. In asthma, allergic airway
inflammation is initiated by IL-33 signaling through ST2, leading to increased IL-4, IL-5, and …

Genome-wide association studies (GWAS) have identified loci reproducibly associated with
pulmonary diseases; however, the molecular mechanism underlying these associations are …

Bronchial asthma is a common inflammatory disease caused by the interaction of genetic
and environmental factors,. Through a genome-wide association study and a replication …

Asthma prevalence has been on the increase, especially in North America compared with
other continents. However, the prevalence of asthma differs worldwide, and in many …