The many flavours of mechanochemistry and its plausible conceptual underpinnings

RT O'Neill, R Boulatov - Nature Reviews Chemistry, 2021 - nature.com
Mechanochemistry describes diverse phenomena in which mechanical load affects
chemical reactivity. The fuzziness of this definition means that it includes processes as …

Characterization techniques of polymer aging: from beginning to end

R Tian, K Li, Y Lin, C Lu, X Duan - Chemical Reviews, 2023 - ACS Publications
Polymers have been widely applied in various fields in the daily routines and the
manufacturing. Despite the awareness of the aggressive and inevitable aging for the …

Experimental quantitation of molecular conditions responsible for flow-induced polymer mechanochemistry

RT O'Neill, R Boulatov - Nature Chemistry, 2023 - nature.com
Fragmentation of macromolecular solutes in rapid flows is of considerable fundamental and
practical importance. The sequence of molecular events preceding chain fracture is poorly …

Toward drug release using polymer mechanochemical disulfide scission

Z Shi, J Wu, Q Song, R Göstl… - Journal of the American …, 2020 - ACS Publications
Traditional pharmacotherapy suffers from multiple drawbacks that hamper patient treatment,
such as the buildup of antibiotic resistances or low drug selectivity and toxicity during …

Coumarin Dimer Is an Effective Photomechanochemical AND Gate for Small-Molecule Release

X He, Y Tian, RT O'Neill, Y Xu, Y Lin… - Journal of the …, 2023 - ACS Publications
Stimulus-responsive gating of chemical reactions is of considerable practical and
conceptual interest. For example, photocleavable protective groups and gating …

Organic neuromorphic devices: Past, present, and future challenges

Y Tuchman, TN Mangoma, P Gkoupidenis… - MRS …, 2020 - cambridge.org
The main goal of the field of neuromorphic computing is to build machines that emulate
aspects of the brain in its ability to perform complex tasks in parallel and with great energy …

The Mechanochemical Synthesis and Activation of Carbon‐Rich π‐Conjugated Materials

M Xuan, C Schumacher, C Bolm, R Göstl… - Advanced …, 2022 - Wiley Online Library
Mechanochemistry uses mechanical force to break, form, and manipulate chemical bonds to
achieve functional transformations and syntheses. Over the last years, many innovative …

Bicyclohexene-peri-naphthalenes: Scalable Synthesis, Diverse Functionalization, Efficient Polymerization, and Facile Mechanoactivation of Their Polymers

J Yang, M Horst, SH Werby, L Cegelski… - Journal of the …, 2020 - ACS Publications
Pursuing polymers that can transform from a nonconjugated to a conjugated state under
mechanical stress to significantly change their properties, we developed a new generation …

2D and 3D inkjet printing of biopharmaceuticals–A review of trends and future perspectives in research and manufacturing

SE Evans, T Harrington, MCR Rivero, E Rognin… - International journal of …, 2021 - Elsevier
There is an ongoing global shift in pharmaceutical business models from small molecule
drugs to biologics. This increase in complexity is in response to advancements in our …

Using mechanochemistry to activate commodity plastics as initiators for radical chain reactions of small organic molecules

K Kubota, J Jiang, Y Kamakura… - Journal of the …, 2023 - ACS Publications
Radical initiators such as azo compounds and organic peroxides have been widely used to
facilitate numerous transformations of free radicals, which enable the efficient synthesis of …