Molecular complexes at euchromatin, heterochromatin and centromeric chromatin

O Morrison, J Thakur - International Journal of Molecular Sciences, 2021 - mdpi.com
Chromatin consists of a complex of DNA and histone proteins as its core components and
plays an important role in both packaging DNA and regulating DNA metabolic pathways …

Epitope imprinted polymeric materials: application in electrochemical detection of disease biomarkers

A Singhal, A Singh, A Shrivastava… - Journal of Materials …, 2023 - pubs.rsc.org
Epitope imprinting is a promising method for creating specialized recognition sites that
resemble natural biorecognition elements. Epitope-imprinted materials have gained a lot of …

[HTML][HTML] Cell-cycle-dependent structural transitions in the human CENP-A nucleosome in vivo

M Bui, EK Dimitriadis, C Hoischen, E An, D Quénet… - Cell, 2012 - cell.com
In eukaryotes, DNA is packaged into chromatin by canonical histone proteins. The
specialized histone H3 variant CENP-A provides an epigenetic and structural basis for …

Tetrameric organization of vertebrate centromeric nucleosomes

EK Dimitriadis, C Weber, RK Gill… - Proceedings of the …, 2010 - National Acad Sciences
Mitosis ensures equal genome segregation in the eukaryotic lineage. This process is
facilitated by microtubule attachment to each chromosome via its centromere. In …

Recent progress in molecular recognition imaging using atomic force microscopy

S Senapati, S Lindsay - Accounts of chemical research, 2016 - ACS Publications
Conspectus Atomic force microscopy (AFM) is an extremely powerful tool in the field of
bionanotechnology because of its ability to image single molecules and make …

Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points

Y Nechemia-Arbely, D Fachinetti, KH Miga… - Journal of Cell …, 2017 - rupress.org
Chromatin assembled with centromere protein A (CENP-A) is the epigenetic mark of
centromere identity. Using new reference models, we now identify sites of CENP-A and …

Nonequilibrium diffusion of active particles bound to a semiflexible polymer network: Simulations and fractional Langevin equation

HT Han, S Joo, T Sakaue, JH Jeon - The Journal of Chemical Physics, 2023 - pubs.aip.org
In a viscoelastic environment, the diffusion of a particle becomes non-Markovian due to the
memory effect. An open question concerns quantitatively explaining how self-propulsion …

Centromere structure and function: lessons from Drosophila

E Kyriacou, P Heun - Genetics, 2023 - academic.oup.com
The fruit fly Drosophila melanogaster serves as a powerful model organism for advancing
our understanding of biological processes, not just by studying its similarities with other …

In situ mapping of biomineral skeletal proteins by molecular recognition imaging with antibody-functionalized AFM tips

B Khurshid, E Lesniewska, L Polacchi, M L'Héronde… - Acta Biomaterialia, 2023 - Elsevier
Spatial localizing of skeletal proteins in biogenic minerals remains a challenge in
biomineralization research. To address this goal, we developed a novel in situ mapping …

Nucleosome-like, single-stranded DNA (ssDNA)-histone octamer complexes and the implication for DNA double strand break repair

NL Adkins, SG Swygert, P Kaur, H Niu… - Journal of Biological …, 2017 - ASBMB
Repair of DNA double strand breaks (DSBs) is key for maintenance of genome integrity.
When DSBs are repaired by homologous recombination, DNA ends can undergo extensive …