[HTML][HTML] Lessons from the host defences of bats, a unique viral reservoir

AT Irving, M Ahn, G Goh, DE Anderson, LF Wang - Nature, 2021 - nature.com
There have been several major outbreaks of emerging viral diseases, including Hendra,
Nipah, Marburg and Ebola virus diseases, severe acute respiratory syndrome (SARS) and …

Intrinsic and extrinsic pathways of apoptosis: Role in cancer development and prognosis

D Kashyap, VK Garg, N Goel - Advances in protein chemistry and structural …, 2021 - Elsevier
Apoptosis, also named programmed cell death, is a fundament process required for
morphogenetic homeostasis during early development and in pathophysiological …

[HTML][HTML] Low-temperature photothermal therapy: strategies and applications

X Yi, QY Duan, FG Wu - Research, 2021 - spj.science.org
Although photothermal therapy (PTT) with the assistance of nanotechnology has been
considered as an indispensable strategy in the biomedical field, it still encounters some …

[HTML][HTML] SARS‐CoV‐2: at the crossroad between aging and neurodegeneration

A Lippi, R Domingues, C Setz, TF Outeiro… - Movement …, 2020 - ncbi.nlm.nih.gov
In December 2019, a pneumonia outbreak associated with a novel form of human
coronavirus was reported in Wuhan, Hubei province, China. 1, 2 As the causative agent of …

Reactive oxygen species, heat stress and oxidative-induced mitochondrial damage. A review

I Belhadj Slimen, T Najar, A Ghram… - International journal …, 2014 - Taylor & Francis
In recent years there has been enormous interest in researching oxidative stress. Reactive
oxygen species (ROS) are derived from the metabolism of oxygen as by-products of cell …

Highly efficient 2D NIR‐II photothermal agent with fenton catalytic activity for cancer synergistic photothermal–chemodynamic therapy

Q Zhang, Q Guo, Q Chen, X Zhao… - Advanced …, 2020 - Wiley Online Library
Photothermal therapy (PTT) has emerged as a promising cancer therapeutic modality with
high therapeutic specificity, however, its therapeutic effectiveness is limited by available high …

[HTML][HTML] Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions

A Jarrahi, M Braun, M Ahluwalia, RV Gupta, M Wilson… - Biomedicines, 2020 - mdpi.com
Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …

Heat shock proteins promote cancer: it's a protection racket

SK Calderwood, J Gong - Trends in biochemical sciences, 2016 - cell.com
Heat shock proteins (HSP) are expressed at high levels in cancer and form a fostering
environment that is essential for tumor development. Here, we review the recent data in this …

[HTML][HTML] HSP70 multi-functionality in cancer

Z Albakova, GA Armeev, LM Kanevskiy, EI Kovalenko… - Cells, 2020 - mdpi.com
The 70-kDa heat shock proteins (HSP70s) are abundantly present in cancer, providing
malignant cells selective advantage by suppressing multiple apoptotic pathways, regulating …

Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease

EJ Goetzl, A Boxer, JB Schwartz, EL Abner… - Neurology, 2015 - AAN Enterprises
Objective: Diverse autolysosomal proteins were quantified in neurally derived blood
exosomes from patients with Alzheimer disease (AD) and controls to investigate disordered …