Objective Inflammation plays a crucial role in the pathogenesis of mild cognitive impairment
(MCI) and Alzheimer's disease (AD). Our study aimed to analyse previous inconsistent …

Tau neuronal and glial pathologies drive the clinical presentation of Alzheimer's disease
and related human tauopathies. There is a growing body of evidence indicating that …

Some forms of mild cognitive impairment (MCI) are the clinical precursors of Alzheimer's
disease (AD), while other MCI types tend to remain stable over-time and do not progress to …

In the current decade, advances in health care are attracting widespread interest due to their
contributions to people longer surviving and fitter lives. Alzheimer's disease (AD) is the …

Introduction A systematic review and meta-analysis was performed regarding the diagnostic
performance of neurofilament light chain (NfL) in CSF and blood. Methods A database …

Progressive cerebral accumulation of tau aggregates is a defining feature of Alzheimer's
disease (AD). A popular theory that seeks to explain the apparent spread of neurofibrillary …

Abstract Chitinase‐3‐like protein 1 (CHI3L1/YKL‐40) has long been known as a biomarker
for early detection of neuroinflammation and disease diagnosis of Alzheimer's disease (AD) …

Introduction Blood-based biomarkers of pathophysiological brain amyloid β (Aβ)
accumulation, particularly for preclinical target and large-scale interventions, are warranted …

Advances in genetic and genomic technologies over the last thirty years have greatly
enhanced our knowledge concerning the genetic architecture of Alzheimer's disease (AD) …

Alzheimer's disease (AD) is a common age-related neurodegenerative disease
characterized by progressive cognitive decline and irreversible memory impairment …