25th anniversary article: Rational design and applications of hydrogels in regenerative medicine

N Annabi, A Tamayol, JA Uquillas, M Akbari… - Advanced …, 2014 - Wiley Online Library
Hydrogels are hydrophilic polymer‐based materials with high water content and physical
characteristics that resemble the native extracellular matrix. Because of their remarkable …

The regenerative role of adipose‐derived stem cells (ADSC) in plastic and reconstructive surgery

N Naderi, EJ Combellack, M Griffin… - International wound …, 2017 - Wiley Online Library
The potential use of stem cell‐based therapies for the repair and regeneration of various
tissues and organs offers a paradigm shift in plastic and reconstructive surgery. The use of …

[HTML][HTML] Engineered neural tissue with aligned, differentiated adipose-derived stem cells promotes peripheral nerve regeneration across a critical sized defect in rat …

M Georgiou, JP Golding, AJ Loughlin, PJ Kingham… - Biomaterials, 2015 - Elsevier
Adipose-derived stem cells were isolated from rats and differentiated to a Schwann cell-like
phenotype in vitro. The differentiated cells (dADSCs) underwent self-alignment in a tethered …

Stimulating the neurotrophic and angiogenic properties of human adipose-derived stem cells enhances nerve repair

PJ Kingham, MK Kolar, LN Novikova… - Stem cells and …, 2014 - liebertpub.com
In future, adipose-derived stem cells (ASC) might be used to treat neurological disorders. In
this study, the neurotrophic and angiogenic properties of human ASC were evaluated, and …

The neurotrophic effects of different human dental mesenchymal stem cells

MK Kolar, VN Itte, PJ Kingham, LN Novikov… - Scientific reports, 2017 - nature.com
The current gold standard treatment for peripheral nerve injury is nerve grafting but this has
disadvantages such as donor site morbidity. New techniques focus on replacing these grafts …

Combination of fibrin-agarose hydrogels and adipose-derived mesenchymal stem cells for peripheral nerve regeneration

V Carriel, J Garrido-Gómez… - Journal of neural …, 2013 - iopscience.iop.org
Objective. The objective was to study the effectiveness of a commercially available collagen
conduit filled with fibrin-agarose hydrogels alone or with fibrin-agarose hydrogels containing …

Schwann cell-like cells: origin and usability for repair and regeneration of the peripheral and central nervous system

A Hopf, DJ Schaefer, DF Kalbermatten, R Guzman… - Cells, 2020 - mdpi.com
Functional recovery after neurotmesis, a complete transection of the nerve fiber, is often poor
and requires a surgical procedure. Especially for longer gaps (> 3 mm), end-to-end suturing …

Targeted stimulation of MSCs in peripheral nerve repair

F Mathot, AY Shin, AJ Van Wijnen - Gene, 2019 - Elsevier
Mesenchymal stem cells (MSCs) have considerable translational potential in a wide variety
of clinical disciplines and are the cellular foundation of individualized treatments of auto …

Peripheral nerve regeneration by secretomes of stem cells from human exfoliated deciduous teeth

Y Sugimura-Wakayama, W Katagiri… - Stem Cells and …, 2015 - liebertpub.com
Peripheral nerve regeneration across nerve gaps is often suboptimal, with poor functional
recovery. Stem cell transplantation-based regenerative therapy is a promising approach for …

Extracellular matrix components in peripheral nerve repair: how to affect neural cellular response and nerve regeneration?

AC De Luca, SP Lacour, W Raffoul… - Neural regeneration …, 2014 - journals.lww.com
Peripheral nerve injury is a serious problem affecting significantly patients' life. Autografts
are the “gold standard” used to repair the injury gap, however, only 50% of patients fully …