[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …
have been used in many different biomedical fields including diagnosis, biosensing and …
Advances in nanomaterial-based targeted drug delivery systems
X Cheng, Q Xie, Y Sun - Frontiers in bioengineering and …, 2023 - frontiersin.org
Nanomaterial-based drug delivery systems (NBDDS) are widely used to improve the safety
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …
The intracellular fate and transport mechanism of shape, size and rigidity varied nanocarriers for understanding their oral delivery efficiency
X Li, SM Jafari, F Zhou, H Hong, X Jia, X Mei, G Hou… - Biomaterials, 2023 - Elsevier
Nanocarriers have become an effective strategy to overcome epithelial absorption barriers.
During the absorption process, the endocytosis mechanisms, cell internalization pathways …
During the absorption process, the endocytosis mechanisms, cell internalization pathways …
Nanomaterials: the new antimicrobial magic bullet
Bacterial infections are a significant cause of mortality and morbidity worldwide, despite
decades of use of numerous existing antibiotics and constant efforts by researchers to …
decades of use of numerous existing antibiotics and constant efforts by researchers to …
Powering mesoporous silica nanoparticles into bioactive nanoplatforms for antibacterial therapies: strategies and challenges
B Li, Y Liao, X Su, S Chen, X Wang, B Shen… - Journal of …, 2023 - Springer
Bacterial infection has been a major threat to worldwide human health, in particular with the
ever-increasing level of antimicrobial resistance. Given the complex microenvironment of …
ever-increasing level of antimicrobial resistance. Given the complex microenvironment of …
[HTML][HTML] Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma
The prognosis of brain cancers such as glioblastoma remains poor despite numerous
advancements in the field of neuro-oncology. The presence of the blood brain barrier (BBB) …
advancements in the field of neuro-oncology. The presence of the blood brain barrier (BBB) …
[HTML][HTML] Inorganic nanoparticles for oral drug delivery: opportunities, barriers, and future perspectives
Oral delivery is the preferred route of drug administration due to patient compliance and
convenience. Despite this, nanomedicines have so far primarily been developed for the …
convenience. Despite this, nanomedicines have so far primarily been developed for the …
[HTML][HTML] Porous silicon embedded in a thermoresponsive hydrogel for intranasal delivery of lipophilic drugs to treat rhinosinusitis
S Bakshi, P Pandey, Y Mohammed, J Wang… - Journal of Controlled …, 2023 - Elsevier
Intranasal delivery is the most preferred route of drug administration for treatment of a range
of nasal conditions including chronic rhinosinusitis (CRS), caused by an infection and …
of nasal conditions including chronic rhinosinusitis (CRS), caused by an infection and …
Nanoparticle-laden contact lens for controlled release of vancomycin with enhanced antibiotic efficacy
Vancomycin is the last resort antibiotic for the treatment of severe bacterial keratitis. Its
clinical application is limited due to its hydrophilicity and high molecular weight. To …
clinical application is limited due to its hydrophilicity and high molecular weight. To …
Mesoporous silica nanoparticles as carrier to overcome bacterial drug resistant barriers
J Zhuang, Y Yu, R Lu - International Journal of Pharmaceutics, 2023 - Elsevier
Antibiotic resistance has become a global threat to health due to abuse of antibiotics. Lots of
existing antibiotics have lost their effect on drug resistant bacteria. Moreover, the discovery …
existing antibiotics have lost their effect on drug resistant bacteria. Moreover, the discovery …