Alzheimer's disease: pathogenesis, diagnostics, and therapeutics

S Tiwari, V Atluri, A Kaushik, A Yndart… - International journal of …, 2019 - Taylor & Francis
Currently, 47 million people live with dementia globally, and it is estimated to increase more
than threefold (~ 131 million) by 2050. Alzheimer's disease (AD) is one of the major …

Design of magnetic hydrogels for hyperthermia and drug delivery

S Ganguly, S Margel - Polymers, 2021 - mdpi.com
Hydrogels are spatially organized hydrophilic polymeric systems that exhibit unique features
in hydrated conditions. Among the hydrogel family, composite hydrogels are a special class …

Magnetic nanoparticles and targeted drug delivering

J Chomoucka, J Drbohlavova, D Huska, V Adam… - Pharmacological …, 2010 - Elsevier
Magnetic nanoparticles (MNPs) are being of great interest due to their unique purposes.
Especially in medicine, application of MNPs is much promising. MNPs have been actively …

Molecular interaction of proteins and peptides with nanoparticles

AA Shemetov, I Nabiev, A Sukhanova - ACS nano, 2012 - ACS Publications
The interaction of proteins in living cells is one of the key processes in the maintenance of
their homeostasis. Introduction of additional agents into the chain of these interactions may …

Nanotechnologies for Alzheimer's disease: diagnosis, therapy, and safety issues

D Brambilla, B Le Droumaguet, J Nicolas… - … , Biology and Medicine, 2011 - Elsevier
Alzheimer's disease (AD) represents the most common form of dementia worldwide,
affecting more than 35 million people. Advances in nanotechnology are beginning to exert a …

Advances in nanomedicines for diagnosis of central nervous system disorders

X Zhang, J Zhou, Z Gu, H Zhang, Q Gong, K Luo - Biomaterials, 2021 - Elsevier
In spite of a great improvement in medical health services and an increase in lifespan, we
have witnessed a skyrocket increase in the incidence of central nervous system (CNS) …

Nanomaterials for reducing amyloid cytotoxicity

M Zhang, X Mao, Y Yu, CX Wang, YL Yang… - Advanced …, 2013 - Wiley Online Library
This review is intended to reflect the recent progress on therapeutic applications of
nanomaterials in amyloid diseases. The progress on anti‐amyloid functions of various …

Protein fibrillation and nanoparticle interactions: opportunities and challenges

M Mahmoudi, HR Kalhor, S Laurent, I Lynch - Nanoscale, 2013 - pubs.rsc.org
Due to their ultra-small size, nanoparticles (NPs) have distinct properties compared with the
bulk form of the same materials. These properties are rapidly revolutionizing many areas of …

Insulin fibrillation: toward strategies for attenuating the process

M Akbarian, R Yousefi, F Farjadian… - Chemical …, 2020 - pubs.rsc.org
Dark days for diabetic patients were transformed into an era of hope when the therapeutic
usage of insulin was discovered. However, those initial glory days changed to being …

Influence of the physiochemical properties of superparamagnetic iron oxide nanoparticles on amyloid β protein fibrillation in solution

M Mahmoudi, F Quinlan-Pluck… - ACS chemical …, 2013 - ACS Publications
Superparamagnetic iron oxide nanoparticles (SPIONs) are recognized as promising
nanodiagnostic materials due to their biocompatibility, unique magnetic properties, and their …