Vaccinology: time to change the paradigm?

CS Benn, AB Fisker, A Rieckmann, S Sørup… - The lancet infectious …, 2020 - thelancet.com
The existing vaccine paradigm assumes that vaccines only protect against the target
infection, that effective vaccines reduce mortality corresponding to the target infection's …

Research trends in rabies vaccine in the last three decades: a bibliometric analysis of global perspective

T Ahmad, Haroon, M Khan, MA Murad… - Human Vaccines & …, 2021 - Taylor & Francis
Introduction Rabies is an infectious zoonotic viral disease which mainly occurs in Africa and
Asia. Dogs are predominantly responsible for rabies transmission contributing up to 99% of …

[HTML][HTML] Non-specific effects of veterinary vaccines: a systematic review

SM Arega, DL Knobel, FN Toka, A Conan - Vaccine, 2022 - Elsevier
The benefits of vaccines have been centred on their specific effects on subsequent
infections by target pathogens. Recent studies, however, have opened up new insights into …

Human rabies: prospects for elimination

J Changalucha, K Hampson, G Jaswant… - CABI …, 2021 - cabidigitallibrary.org
Almost half of all countries in the world are effectively free of human deaths from dog-
mediated rabies. But the disease still affects people in low-and middle-income countries …

Bayesian modeling of post-vaccination serological data suggests that yearly vaccination of dog aged< 2 years old is efficient to stop rabies circulation in Cambodia

H Auerswald, J Guillebaud, B Durand… - PLoS Neglected …, 2024 - journals.plos.org
Rabies control remains challenging in low and middle-income countries, mostly due to lack
of financial resources, rapid turnover of dog populations and poor accessibility to dogs …

Risks related to a possible reduction of the waiting period for dogs after rabies antibody titration to 30 days compared with 90 days of the current EU legislative regime

European Food Safety Authority (EFSA)… - EFSA …, 2022 - Wiley Online Library
EFSA received a mandate from the European Commission to assess the risks related to a
possible reduction of the waiting period after rabies antibody titration test to 30 days …

Puppies as the primary causal animal for human rabies cases: three-year prospective study of human rabies in the Philippines

N Saito, KL Inton, JD Mauhay, RM Solante… - Frontiers in …, 2024 - frontiersin.org
Introduction While rabies remains a global concern, detailed studies on human rabies,
particularly regarding causal animals and the reasons for not receiving postexposure …

Factors Involved in the Immunological Protection against Rabies Virus in Dogs in Spain

MD Manzano, J Cereza, J García, LJ Yus, JJ Badiola… - Vaccines, 2024 - mdpi.com
Rabies, a viral disease spread by infected animal bites that causes encephalitis in humans
and other mammals, is a neglected infectious disease present on all continents except …

Rabies Virus Seroprevalence among Dogs in Limpopo National Park and the Phylogenetic Analyses of Rabies Viruses in Mozambique

M Mapatse, E Ngoepe, D Abernethy, JM Fafetine… - Pathogens, 2022 - mdpi.com
Rabies is considered a neglected disease among many developing Asian and African
countries, including Mozambique, where its re-emergence is often attributed to low dog …

Sex-differential non-specific effects of adjuvanted and non-adjuvanted rabies vaccines versus placebo on all-cause mortality in dogs (NERVE-Dog study): a study …

DL Knobel, A Conan, FN Toka, SM Arega… - BMC Veterinary …, 2022 - Springer
Background It has been proposed that childhood vaccines in high-mortality populations may
have substantial impacts on mortality rates that are not explained by the prevention of …