The intestinal barrier protects the host against gut microbes, food antigens, and toxins
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …

The human gastrointestinal tract (GI) harbors a diverse population of microbial life that
continually shapes host pathophysiological responses. Despite readily available abundant …

Inflammatory diseases, whether caused by excessive stress on certain tissues/parts of the
body or arising from infections accompanying autoimmune or secondary diseases, have …

The organoids represent one of the greatest revolutions in the biomedical field in the past
decade. This three-dimensional (3D) micro-organ cultured in vitro has a structure highly …

Evidence from recent epidemiological data suggests that the patient population with
inflammatory bowel disease (IBD) is chronologically aging. As these individuals become …

Background Inflammatory bowel disease (IBD) is a chronic idiopathic disease that is
characterized by inflammation of the gastrointestinal tract. Proper management of IBD …

Background: Pregnancy is often described as an immune-tolerant state, and a disease
modulatory role for pregnancy on inflammatory bowel disease (IBD) has been suggested …

With increasing urbanization and industrialization, the prevalence of inflammatory bowel
diseases (IBDs) has steadily been rising over the past two decades. IBD involves flares of …

Inflammatory bowel disease (IBD) is an inflammatory disorder that affects the gastrointestinal
tract. IBD has become an increasingly common condition in both developed and developing …

Abstract Background and Aims Crohn's disease (CD) is characterized by an overabundance
of epithelial cell death and an imbalance in microflora, both of which contribute to the …