Stroke pathology and its treatments conventionally focus on the brain. Probing inflammation,
a critical secondary cell death mechanism in stroke, has been largely relegated to the brain …

Background Whether thrombectomy alone is equally as effective as intravenous alteplase
plus thrombectomy remains controversial. We aimed to determine whether thrombectomy …

Ischemic stroke is a common neurologic condition and can lead to significant long term
disability and death. Observational studies have demonstrated worse outcomes in patients …

Background and Purpose: Symptomatic intracranial hemorrhage (sICH), potentially
associated with poor prognosis, is a major complication of endovascular thrombectomy …

Background and Purpose—If anterior circulation large vessel occlusion acute ischemic
stroke patients presenting with ASPECTS 0–5 (Alberta Stroke Program Early CT Score) …

Background Hemorrhagic transformation (HT) is a severe complication occurring in acute
ischemic stroke (AIS) patients. Stress hyperglycemia is frequent in patients with acute illness …

Background Whether pretreatment with intravenous thrombolysis prior to mechanical
thrombectomy (IVT+ MTE) adds additional benefit over direct mechanical thrombectomy …

Background and Purpose: This study evaluates the benefit of endovascular treatment (EVT)
for patients with extensive baseline stroke compared with best medical treatment. Methods …

Background and Purpose—Parenchymal hematoma (PH) is a rare but dreadful complication
of acute ischemic stroke with unclear underlying mechanisms. We aimed to study the …

Background: Parenchymal hematoma (PH) is a major complication after endovascular
treatment (EVT) for ischemic stroke. The hypoperfusion intensity ratio (HIR) represents a …