Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signalling

ME Liechti - Swiss medical weekly, 2015 - edoc.unibas.ch
Novel psychoactive substances are newly used designer drugs (" internet drugs"," research
chemicals"," legal highs") potentially posing similar health risks to classic illicit substances …

The health effects of ecstasy: a literature review

LR Gowing, SM HENRY‐EDWARDS… - Drug and alcohol …, 2002 - Wiley Online Library
Abstract Ecstasy (3, 4‐methylenedioxymethamphetamine, MDMA) is the third most used
illicit drug, after cannabis and amphetamines. There has been considerable interest in the …

[图书][B] Karch's pathology of drug abuse

SB Karch, O Drummer - 2008 - taylorfrancis.com
Written for practitioners in the field, this critically acclaimed bestseller provides authoritative
information focused on the investigation of drug-related deaths and practical approaches to …

Monoamine transporter and receptor interaction profiles of a new series of designer cathinones

LD Simmler, A Rickli, MC Hoener, ME Liechti - Neuropharmacology, 2014 - Elsevier
Psychoactive β-keto amphetamines (cathinones) are sold as “bath salts” or “legal highs” and
recreationally abused. We characterized the pharmacology of a new series of cathinones …

[HTML][HTML] Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport

JU Fog, H Khoshbouei, M Holy, WA Owens… - Neuron, 2006 - cell.com
Efflux of dopamine through the dopamine transporter (DAT) is critical for the
psychostimulatory properties of amphetamines, but the underlying mechanism is unclear …

Cocaine increases dopamine uptake and cell surface expression of dopamine transporters

LC Daws, PD Callaghan, JA Morón, KM Kahlig… - Biochemical and …, 2002 - Elsevier
In HEK 293 cells expressing the human dopamine transporter (DAT), a 10-min incubation
with 10 μM cocaine followed by extensive washing resulted in a 30% increase in [3H] …

Neurobiology of 3, 4-methylenedioxypyrovalerone (MDPV) and α-pyrrolidinovalerophenone (α-PVP)

RA Glennon, R Young - Brain research bulletin, 2016 - Elsevier
Synthetic cathinones are analogs of cathinone or β-ketoamphetamine–the major
psychostimulant component of the shrub Catha edulis or khat. Cathinone analogs–though …

Metabolism of designer drugs of abuse

RF Staack, HH Maurer - Current drug metabolism, 2005 - ingentaconnect.com
Abuse of designer drugs is widespread among young people, especially in the so-called
“dance club scene” or “rave scene”, worldwide. Severe and even fatal poisonings have been …

[HTML][HTML] The health effect of psychostimulants: a literature review

T Favrod-Coune, B Broers - Pharmaceuticals, 2010 - mdpi.com
Prevalence of psychostimulant use is high, and raising in several countries. Nicotine is the
legal stimulant causing the most important public health impact. Cocaine ranks among the …

The toxicology of new psychoactive substances: synthetic cathinones and phenylethylamines

E Tyrkkö, M Andersson… - Therapeutic drug …, 2016 - journals.lww.com
Background: New psychoactive substances (NPSs) are substitutes for classical drugs of
abuse and there are now compounds available from all groups of classical drugs of abuse …