COVID-19 is the current public health threat all over the world. Unfortunately, there is no
specific prevention and treatment strategy for this disease. We aim to explore the potential …

Angiotensin-converting enzyme (ACE) 2 is a homolog to the carboxypeptidase ACE, which
generates angiotensin II, the main active peptide of renin–angiotensin system (RAS). After …

Angiotensin-converting enzyme 2 (ACE2) is the cellular receptor for severe acute respiratory
syndrome–coronavirus (SARS-CoV) and the new coronavirus (SARS-CoV-2) that is causing …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has swept over the world in
the past months, causing significant loss of life and consequences to human health …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

The last decade has seen the discovery of several new components of the renin-angiotensin
system (RAS). Among them, angiotensin converting enzyme-2 (ACE2) and the Mas receptor …

The protease renin is the key enzyme of the renin-angiotensin-aldosterone cascade, which
is relevant under both physiological and pathophysiological settings. The kidney is the only …

Aerobic exercise training leads to a physiological, nonpathological left ventricular
hypertrophy; however, the underlying biochemical and molecular mechanisms of …

Ever since its outbreak, Corona Virus Disease 2019 (COVID-19) caused by SARS-CoV-2
has affected more than 26 million individuals in more than 200 countries. Although the …

Angiotensin-converting enzyme (ACE) enhances the proliferation and migration of
pulmonary artery smooth muscle cells (PASMCs), which contribute to the pathogenesis of …