Engineering of relevant photodynamic processes through structural modifications of metallotetrapyrrolic photosensitizers

JM Dąbrowski, B Pucelik, A Regiel-Futyra… - Coordination Chemistry …, 2016 - Elsevier
Applications of metalloporphyrins and related molecules have been extensively pursued in
the context of photodynamic therapy of cancer (PDT) and other biomedical applications. This …

A concise review on cancer treatment methods and delivery systems

E Bidram, Y Esmaeili, H Ranji-Burachaloo… - Journal of Drug Delivery …, 2019 - Elsevier
The ultimate purpose of current cancer research is to develop a comprehensive treatment for
cancer. Recent studies have shown an increased interest in investigating the capacity of …

[HTML][HTML] Encapsulation of Ru (II) polypyridine complexes for tumor-targeted anticancer therapy

J Karges - BME frontiers, 2023 - spj.science.org
Ru (II) polypyridine complexes have attracted much attention as anticancer agents because
of their unique photophysical, photochemical, and biological properties. Despite their …

Targeted photodynamic therapy as potential treatment modality for the eradication of colon cancer and colon cancer stem cells

N Hodgkinson, CA Kruger, H Abrahamse - Tumor Biology, 2017 - journals.sagepub.com
Colorectal cancer is commonly treated by tumour resection, as chemotherapy and radiation
have proven to be less effective, especially if the tumour has metastasized. Resistance to …

Photosensitizer antibody–drug conjugates: past, present, and future

J Sandland, RW Boyle - Bioconjugate chemistry, 2019 - ACS Publications
This Review aims to highlight key aspects of tetrapyrrole-based antibody–drug conjugates
(ADCs) and significant developments in the field since 2010. Many new conjugation …

[HTML][HTML] Latest innovations and nanotechnologies with curcumin as a nature-inspired photosensitizer applied in the photodynamic therapy of cancer

LM Ailioaie, C Ailioaie, G Litscher - Pharmaceutics, 2021 - mdpi.com
In the context of the high incidence of cancer worldwide, state-of-the-art photodynamic
therapy (PDT) has entered as a usual protocol of attempting to eradicate cancer as a …

[HTML][HTML] Utilisation of targeted nanoparticle photosensitiser drug delivery systems for the enhancement of photodynamic therapy

CA Kruger, H Abrahamse - Molecules, 2018 - mdpi.com
The cancer incidence world-wide has caused an increase in the demand for effective forms
of treatment. One unconventional form of treatment for cancer is photodynamic therapy …

[HTML][HTML] Effective gold nanoparticle-antibody-mediated drug delivery for photodynamic therapy of lung cancer stem cells

A Crous, H Abrahamse - International Journal of Molecular Sciences, 2020 - mdpi.com
Cancer stem cells (CSCs) are a leading contributor to lung cancer mortality rates. CSCs are
responsible for tumor growth and recurrence through inhibition of drug-induced cell death …

Polymeric encapsulation of a ruthenium polypyridine complex for tumor targeted one-and two-photon photodynamic therapy

J Karges, J Li, L Zeng, H Chao… - ACS Applied Materials & …, 2020 - ACS Publications
Photodynamic therapy is a medical technique, which is gaining increasing attention to treat
various types of cancer. Among the investigated classes of photosensitizers (PSs), the use of …

[HTML][HTML] Research progress of conjugated nanomedicine for cancer treatment

B Zhao, S Chen, Y Hong, L Jia, Y Zhou, X He, Y Wang… - Pharmaceutics, 2022 - mdpi.com
The conventional cancer therapeutic modalities include surgery, chemotherapy and
radiotherapy. Although immunotherapy and targeted therapy are also widely used in cancer …