Plasmodium vivax in the era of the shrinking P. falciparum map

RN Price, RJ Commons, KE Battle, K Thriemer… - Trends in …, 2020 - cell.com
Plasmodium vivax is an important cause of malaria, associated with a significant public
health burden. Whilst enhanced malaria-control activities have successfully reduced the …

malERA: an updated research agenda for malaria elimination and eradication

RN Rabinovich, C Drakeley, AA Djimde, BF Hall… - PLoS …, 2017 - journals.plos.org
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

[HTML][HTML] Estimating the proportion of Plasmodium vivax recurrences caused by relapse: a systematic review and meta-analysis

RJ Commons, JA Simpson, J Watson… - The American journal …, 2020 - ncbi.nlm.nih.gov
Plasmodium vivax and Plasmodium ovale form dormant liver hypnozoites that can reactivate
weeks to months following initial infection. Malaria recurrences caused by relapses are an …

Resolving the cause of recurrent Plasmodium vivax malaria probabilistically

AR Taylor, JA Watson, CS Chu, K Puaprasert… - Nature …, 2019 - nature.com
Relapses arising from dormant liver-stage Plasmodium vivax parasites (hypnozoites) are a
major cause of vivax malaria. However, in endemic areas, a recurrent blood-stage infection …

8-Aminoquinoline therapy for latent malaria

JK Baird - Clinical Microbiology Reviews, 2019 - Am Soc Microbiol
The technical genesis and practice of 8-aminoquinoline therapy of latent malaria offer
singular scientific, clinical, and public health insights. The 8-aminoquinolines brought …

Plasmodium vivax Transmission in Africa

RE Howes, RC Reiner Jr, KE Battle… - PLoS neglected …, 2015 - journals.plos.org
Malaria in sub-Saharan Africa has historically been almost exclusively attributed to
Plasmodium falciparum (Pf). Current diagnostic and surveillance systems in much of sub …

Association of impaired cytochrome P450 2D6 activity genotype and phenotype with therapeutic efficacy of primaquine treatment for latent Plasmodium vivax malaria

JK Baird, M Louisa, R Noviyanti, L Ekawati… - JAMA Network …, 2018 - jamanetwork.com
Importance Latent hepaticPlasmodium vivaxhypnozoites provoke repeated clinical attacks
called relapses. Only primaquine phosphate kills hypnozoites, and its therapeutic activity …

[HTML][HTML] Plasmodium vivax gametocytes and transmission

S Bantuchai, H Imad, W Nguitragool - Parasitology International, 2022 - Elsevier
Malaria elimination means cessation of parasite transmission. At present, the declining
malaria incidence in many countries has made elimination a feasible goal. Transmission …

Plasmodium vivax Latent Liver Stage Infection and Relapse: Biological Insights and New Experimental Tools

C Schäfer, G Zanghi, AM Vaughan… - Annual Review of …, 2021 - annualreviews.org
Plasmodium vivax is the most widespread human malaria parasite, in part because it can
form latent liver stages known as hypnozoites after transmission by female anopheline …

[HTML][HTML] Monitoring Plasmodium vivax resistance to antimalarials: Persisting challenges and future directions

MU Ferreira, TN de Sousa, GW Rangel… - International Journal for …, 2021 - Elsevier
Emerging antimalarial drug resistance may undermine current efforts to control and
eliminate Plasmodium vivax, the most geographically widespread yet neglected human …