The viral class II membrane fusion machinery: divergent evolution from an ancestral heterodimer

P Guardado-Calvo, FA Rey - Viruses, 2021 - mdpi.com
A key step during the entry of enveloped viruses into cells is the merger of viral and cell lipid
bilayers. This process is driven by a dedicated membrane fusion protein (MFP) present at …

Zoonotic Hantaviridae with Global Public Health Significance

RX Chen, HY Gong, X Wang, MH Sun, YF Ji, SM Tan… - Viruses, 2023 - mdpi.com
Hantaviridae currently encompasses seven genera and 53 species. Multiple hantaviruses
such as Hantaan virus, Seoul virus, Dobrava-Belgrade virus, Puumala virus, Andes virus …

Regulation and functions of the NLRP3 inflammasome in RNA virus infection

Z Yue, X Zhang, Y Gu, Y Liu, LM Lan, Y Liu… - Frontiers in Cellular …, 2024 - frontiersin.org
Virus infection is one of the greatest threats to human life and health. In response to viral
infection, the host's innate immune system triggers an antiviral immune response mostly …

An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo

Y Zhao, N Zhao, Y Cai, H Zhang, J Li, J Liu… - Frontiers in Cellular …, 2022 - frontiersin.org
Hantaan virus (HTNV) is the etiological pathogen of hemorrhagic fever with renal syndrome
in East Asia. There are currently no effective therapeutics approved for HTNV and other …

Sin Nombre virus and the emergence of other hantaviruses: a review of the biology, ecology, and disease of a zoonotic pathogen

AT Jacob, BM Ziegler, SM Farha, LR Vivian, CA Zilinski… - Biology, 2023 - mdpi.com
Simple Summary In this review, we provide updates on Sin Nombre virus (SNV) and other
New World hantaviruses. We discuss the history of SNV, its biology and relatedness to other …

Comprehensive computational analysis reveals YXXφ [I/L/M/F/V] motif and YXXφ-like tetrapeptides across HFRS causing hantaviruses and their association with viral …

F Noor, UA Ashfaq, M Asif, MM Adeel… - Frontiers in …, 2022 - frontiersin.org
Hemorrhagic fever with renal syndrome (HFRS) is an acute zoonotic disease transmitted
through aerosolized excrement of rodents. The etiology of HFRS is complex due to the …

[HTML][HTML] STING strengthens host anti-hantaviral immunity through an interferon-independent pathway

K Wang, J Zhang, Y Yang, Y Si, Z Zhou, X Zhu, S Wu… - Virologica Sinica, 2023 - Elsevier
Hantaan virus (HTNV), the prototype virus of hantavirus, could escape innate immunity by
restraining type I interferon (IFN) responses. It is largely unknown whether there existed …

Choclo virus (CHOV) recovered from deep metatranscriptomics of archived frozen tissues in natural history biorepositories

PS Salazar-Hamm, WL Johnson… - PLOS Neglected …, 2024 - journals.plos.org
Background Hantaviruses are negative-stranded RNA viruses that can sometimes cause
severe disease in humans; however, they are maintained in mammalian host populations …

Integrativesubtractive proteomics, immunoinformatics, docking, and simulation approaches reveal candidate vaccine against Sin Nombre orthohantavirus

AB Alabbas - Frontiers in Immunology, 2022 - frontiersin.org
The emergence of Sin Nombre orthohantavirus, an etiological agent of hantavirus
cardiopulmonary syndrome, exacerbates the situation and imposes a heavy financial …

Amugulang virus, a novel hantavirus harboured by small rodents in Hulunbuir, China

X Han, L Zhang, M Zhang, Q Xin, Y Zhao… - Emerging Microbes & …, 2024 - Taylor & Francis
The Hulunbuir region, known for its diverse terrain and rich wildlife, is a hotspot for various
natural epidemic diseases. Between 2021 and 2023, we collected 885 wild rodent samples …