Extrapineal melatonin: sources, regulation, and potential functions

D Acuña-Castroviejo, G Escames, C Venegas… - Cellular and molecular …, 2014 - Springer
Endogenous melatonin is synthesized from tryptophan via 5-hydroxytryptamine. It is
considered an indoleamine from a biochemical point of view because the melatonin …

Applications for α-lactalbumin in human nutrition

DK Layman, B Lönnerdal, JD Fernstrom - Nutrition reviews, 2018 - academic.oup.com
Abstract α-Lactalbumin is a whey protein that constitutes approximately 22% of the proteins
in human milk and approximately 3.5% of those in bovine milk. Within the mammary gland, α …

Development of the circadian system in early life: maternal and environmental factors

SD Wong, KP Wright Jr, RL Spencer, C Vetter… - Journal of physiological …, 2022 - Springer
In humans, an adaptable internal biological system generates circadian rhythms that
maintain synchronicity of behavior and physiology with the changing demands of the 24-h …

Circadian variation in human milk composition, a systematic review

MF Italianer, EFG Naninck, JA Roelants… - Nutrients, 2020 - mdpi.com
Background: Breastfeeding is considered the most optimal mode of feeding for neonates
and mothers. Human milk changes over the course of lactation in order to perfectly suit the …

Food as a circadian time cue—evidence from human studies

P Lewis, H Oster, HW Korf, RG Foster… - Nature Reviews …, 2020 - nature.com
Meal timing and composition are frequently reported in the literature as zeitgebers (that is,
time cues) for the circadian system of humans and animal models, albeit secondary to light …

Human milk composition promotes optimal infant growth, development and health

S Perrella, Z Gridneva, CT Lai, L Stinson… - Seminars in …, 2021 - Elsevier
Human milk is a living dynamic fluid that promotes optimal nutrition and development of the
infant and impacts health across the lifespan. This review reports on the diverse range of …

Effects of tryptophan loading on human cognition, mood, and sleep

BY Silber, JAJ Schmitt - Neuroscience & biobehavioral reviews, 2010 - Elsevier
Modulating central serotonergic function by acute tryptophan depletion (ATD) has provided
the fundamental insights into which cognitive functions are influenced by serotonin. It may …

Breastfeeding may improve nocturnal sleep and reduce infantile colic: potential role of breast milk melatonin

A Cohen Engler, A Hadash, N Shehadeh… - European journal of …, 2012 - Springer
Melatonin is secreted during the night in adults but not in infants. It has a hypnotic effect as
well as a relaxing effect on the smooth muscle of the gastrointestinal tract. It is plausible that …

Tryptophan-enriched cereal intake improves nocturnal sleep, melatonin, serotonin, and total antioxidant capacity levels and mood in elderly humans

R Bravo, S Matito, J Cubero, SD Paredes, L Franco… - Age, 2013 - Springer
Melatonin and serotonin rhythms, which exhibit a close association with the endogenous
circadian component of sleep, are attenuated with increasing age. This decrease seems to …

Oxidative stress of the newborn in the pre‐and postnatal period and the clinical utility of melatonin

E Gitto, S Pellegrino, P Gitto, I Barberi… - Journal of pineal …, 2009 - Wiley Online Library
Newborns, and especially those delivered preterm, are probably more prone to oxidative
stress than individuals later in life. Also during pregnancy, increased oxygen demand …