[HTML][HTML] Bone/cartilage targeted hydrogel: Strategies and applications
H Zhang, S Wu, W Chen, Y Hu, Z Geng, J Su - Bioactive materials, 2023 - Elsevier
The skeletal system is responsible for weight-bearing, organ protection, and movement.
Bone diseases caused by trauma, infection, and aging can seriously affect a patient's quality …
Bone diseases caused by trauma, infection, and aging can seriously affect a patient's quality …
[HTML][HTML] Recent approaches for enhancing the performance of dissolving microneedles in drug delivery applications
Dissolving microneedles (dMNs) are promising versatile drug delivery systems for the
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …
Dissolvable polymer microneedles for drug delivery and diagnostics
Dissolvable transdermal microneedles (μND) are promising micro-devices used to transport
a wide selection of active compounds into the skin. To provide an effective therapeutic …
a wide selection of active compounds into the skin. To provide an effective therapeutic …
Microneedles: a new frontier in nanomedicine delivery
This review aims to concisely chart the development of two individual research fields,
namely nanomedicines, with specific emphasis on nanoparticles (NP) and microparticles …
namely nanomedicines, with specific emphasis on nanoparticles (NP) and microparticles …
Dissolving microneedle patches for dermal vaccination
The dermal route is an attractive route for vaccine delivery due to the easy skin accessibility
and a dense network of immune cells in the skin. The development of microneedles is …
and a dense network of immune cells in the skin. The development of microneedles is …
Recent advances in the design of polymeric microneedles for transdermal drug delivery and biosensing
M Wang, L Hu, C Xu - Lab on a Chip, 2017 - pubs.rsc.org
Microneedles are an efficient and minimally invasive approach to transdermal drug delivery
and extraction of skin interstitial fluid. Compared to solid microneedles made of silicon …
and extraction of skin interstitial fluid. Compared to solid microneedles made of silicon …
Microneedles for gene and drug delivery in skin cancer therapy
D Zhi, T Yang, T Zhang, M Yang, S Zhang… - Journal of Controlled …, 2021 - Elsevier
The success of skin cancer treatment is severely limited in the route of administration
because most genes and drugs cannot break through the excellent stratum corneum (SC) …
because most genes and drugs cannot break through the excellent stratum corneum (SC) …
[HTML][HTML] Transdermal delivery of gentamicin using dissolving microneedle arrays for potential treatment of neonatal sepsis
P González-Vázquez, E Larrañeta… - Journal of Controlled …, 2017 - Elsevier
Neonatal infections are a leading cause of childhood mortality in low-resource settings.
World Health Organization guidelines for outpatient treatment of possible serious bacterial …
World Health Organization guidelines for outpatient treatment of possible serious bacterial …
DNA vaccination via RALA nanoparticles in a microneedle delivery system induces a potent immune response against the endogenous prostate cancer stem cell …
Castrate resistant prostate cancer (CRPC) remains a major challenge for healthcare
professionals. Immunotherapeutic approaches, including DNA vaccination, hold the …
professionals. Immunotherapeutic approaches, including DNA vaccination, hold the …
Microneedle-mediated transdermal delivery of bevacizumab
AJ Courtenay, MTC McCrudden… - Molecular …, 2018 - ACS Publications
Bevacizumab is a recombinant humanized monoclonal antibody used clinically as a
combination chemotherapeutic. Antibody therapeutics are usually formulated as parenteral …
combination chemotherapeutic. Antibody therapeutics are usually formulated as parenteral …