With the emergence of RNA sequencing (RNA-seq) technologies, RNA-based biomolecules
hold expanded promise for their diagnostic, prognostic and therapeutic applicability in …

The last decade has witnessed a steady embrace of genomic and personalized medicine by
senior government officials, industry leadership, health care providers, and the public …

CHAIR: Costanzo MR: Midwest Heart Foundation, Lombard Illinois, USA TASK FORCE 1:
Dipchand A: Hospital for Sick Children, Toronto Ontario, Canada; Starling R: Cleveland …

It is challenging to monitor the health of transplanted organs, particularly with respect to
rejection by the host immune system. Because transplanted organs have genomes that are …

Personalized medicine is a broad and rapidly advancing field of health care that is informed
by each person's unique clinical, genetic, genomic, and environmental information …

Background Endomyocardial biopsy is the standard method of monitoring for rejection in
recipients of a cardiac transplant. However, this procedure is uncomfortable, and there are …

Early diagnosis of allograft rejection helps to improve the immune‐related management of
transplant recipients. The clinically‐used core needle biopsy method is invasive and subject …

Aims A non-invasive gene-expression profiling (GEP) test for rejection surveillance of heart
transplant recipients originated in the USA. A European-based study, Cardiac Allograft …

Since the completion of the Human Genome Project in 2003, genomic sequencing has
become a prominent tool used by diverse disciplines in modern science. In the past 20 …

Background—The endomyocardial biopsy (EMB) is considered the gold standard in
rejection surveillance post cardiac transplant, but is invasive, with risk of complications. A …