Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2

K Gao, R Wang, J Chen, L Cheng, J Frishcosy… - Chemical …, 2022 - ACS Publications
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …

Interferon-inducer antivirals: Potential candidates to combat COVID-19

A Bagheri, SMI Moezzi, P Mosaddeghi… - International …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is an infective disease generated by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Given the pandemic urgency and …

A molecular docking study of EGCG and theaflavin digallate with the druggable targets of SARS-CoV-2

S Mhatre, S Naik, V Patravale - Computers in biology and medicine, 2021 - Elsevier
Background COVID-19 is an infectious disease caused by a novel positive-sense single-
stranded RNA coronavirus called as SARS-CoV-2. This viral disease is known to infect the …

[PDF][PDF] State-of-the-art tools unveil potent drug targets amongst clinically approved drugs to inhibit helicase in SARS-CoV-2

JF Borgio, HS Alsuwat, WM Al Otaibi… - Archives of Medical …, 2020 - termedia.pl
State-of-the-art tools unveil potent drug targets amongst clinically approved drugs to inhibit
helicase in SARS-CoV-2 Page 1 Creative Commons licenses: This is an Open Access article …

“Celebrating old age”: an obsolete expression during the COVID-19 pandemic? Medical, social, psychological, and religious consequences of home isolation and …

A Burlacu, I Mavrichi, R Crisan-Dabija… - Archives of medical …, 2020 - pmc.ncbi.nlm.nih.gov
Since epidemiological arguments favouring self-isolation during the COVID-19 pandemic
are widely recommended, the consequences of social isolation/loneliness of older people …

[HTML][HTML] Genome composition and genetic characterization of SARS-CoV-2

AM Al-Qaaneh, T Alshammari, R Aldahhan… - Saudi journal of …, 2021 - Elsevier
SARS-CoV-2 is a type of Betacoronaviruses responsible for COVID-19 pandemic disease,
with more than 1.745 million fatalities globally as of December-2020. Genetically, it is …

Bioinformatics approach for the construction of multiple epitope vaccine against omicron variant of SARS-CoV-2

S Zaib, F Akram, ST Liaqat, MZ Altaf, I Khan… - Scientific Reports, 2022 - nature.com
Abstract The World Health Organization categorized SARS-CoV-2 as a variant of concern,
having numerous mutations in spike protein, which have been found to evade the effect of …

Structure-based virtual screening and biochemical validation to discover a potential inhibitor of the SARS-CoV-2 main protease

A Gupta, C Rani, P Pant, V Vijayan, N Vikram… - ACS …, 2020 - ACS Publications
The recent pandemic caused by SARS-CoV-2 has led the world to a standstill, causing a
medical and economic crisis worldwide. This crisis has triggered an urgent need to discover …

Evaluation of nonnatural L-iminosugar C, C-glycosides, a new class of C-branched iminosugars, as glycosidase inhibitors

J Désiré, Z Debbah, D Gueyrard, J Marrot, Y Blériot… - Carbohydrate …, 2023 - Elsevier
Capitalizing on a previously developed Staudinger/azaWittig/Grignard (SAWG)-ring
contraction sequence that furnished protected six-membered L-iminosugar C, C-glycosides …

Synthesis and glycosidase inhibition of 5-C-alkyl-DNJ and 5-C-alkyl-L-ido-DNJ derivatives

TT Lu, Y Shimadate, B Cheng, U Kanekiyo… - European Journal of …, 2021 - Elsevier
C-Alkyl-DNJ and 5-C-alkyl-l-ido-DNJ derivatives have been designed and synthesized
efficiently from an l-sorbose-derived cyclic nitrone. The DNJ and l-ido-DNJ derivatives with C …