[HTML][HTML] Nanocarrier-Based, ocular drug delivery: Challenges, prospects, and the therapeutic landscape in the United Arab Emirates

SA AlYabhouni, MS Mozumder, N Hassan… - International Journal of …, 2024 - Elsevier
Human eyes have the most complex and advanced physiological defense barriers. Due to
these barriers, efficient delivery of ocular drugs is a major challenge in the treatment of eye …

The inverse association between DNA gaps and HbA1c levels in type 2 diabetes mellitus

J Thongsroy, A Mutirangura - Scientific Reports, 2023 - nature.com
Naturally occurring DNA gaps have been observed in eukaryotic DNA, including DNA in
nondividing cells. These DNA gaps are found less frequently in chronologically aging yeast …

Diagnostic biomarker for type 2 diabetic peripheral neuropathy via comprehensive bioinformatics analysis

X Chen, Q Liu, N Chen, J Ma, X Wu, H Zhang… - Journal of …, 2024 - Wiley Online Library
Background Diabetic peripheral neuropathy (DPN) is a common complication of Type 2
diabetes mellitus (T2DM), which frequently results in disabling neuropathic pain and lower …

Diabetes-Related Microvascular Complications in Primary Health Care Settings in the West Bank, Palestine

M Dweib, N El Sharif - Journal of Clinical Medicine, 2023 - mdpi.com
Background: Worldwide, retinopathy, nephropathy, and neuropathy are the major diabetes-
related microvascular complications. In Palestine, a low-middle-income country, diabetes is …

Genetic Variability in VEGFA Gene Influences the Effectiveness of Tennis Elbow Therapy with PRP: A Two-Year Prospective Cohort Study

P Niemiec, A Jarosz, A Balcerzyk-Matić… - International Journal of …, 2023 - mdpi.com
Vascular endothelial growth factor (VEGF) is implicated in both the etiology of tendinopathy
and its healing process. Polymorphic variants of the VEGFA gene exhibit varied expression …

Decreased Alu methylation in type 2 diabetes mellitus patients increases HbA1c levels

J Thongsroy, A Mutirangura - Journal of Clinical Laboratory …, 2023 - Wiley Online Library
Introduction Alu hypomethylation is a common epigenetic process that promotes genomic
instability with aging phenotypes, which leads to type 2 diabetes mellitus (type 2 DM) …

Genetic variations of tumor necrosis factor-α and prostaglandin-endoperoxide synthase 2 genes among Egyptian patients with type 2 diabetes mellitus and diabetic …

AS Khalifa, A Elshebiny, EM Eed, MG Elhelbawy… - Gene Reports, 2022 - Elsevier
Objectives The current study aimed to determine whether genetic differences in the tumor
necrosis factor-α (TNF-α) and prostaglandin-endoperoxide synthase 2 (PTG2) genes are …

Meta-analysis of genes and genetic variants implicated in Type II diabetes mellitus, diabetic retinopathy, and diabetic nephropathy

AN Rizza, N Lenin, Y Ramaswamy… - Human Gene, 2025 - Elsevier
Meta-analysis is a popular technique for aggregating evidence from a variety of similar
studies for collective comparison. This paper presents data on genes and genetic variants …

Whole‐genome sequencing study to identify candidate markers indicating susceptibility to type 2 diabetes in Bama miniature pigs

M Niu, Y Zhao, Y Jia, L Xiang, X Dai… - Animal Models and …, 2023 - Wiley Online Library
Background Hundreds of single‐nucleotide polymorphism (SNP) sites have been found to
be potential genetic markers of type 2 diabetes mellitus (T2DM). However, SNPs related to …

Identification of Potential EGFR Inhibitors for Type 2 Diabetes and Pancreatic Cancer Treatment: A Computational Approach

R Romero - bioRxiv, 2023 - biorxiv.org
This study conducted a differential gene expression analysis in two independent studies of
type 2 diabetes using pancreatic samples, specifically Langerhans cells. Through protein …