Transcription initiation is a key regulatory step in the control of gene expression. Formation
of a preinitiation complex at the right time and at the right promoter is a prerequisite to …

Enhancer-blocking insulators are DNA elements that disrupt the communication between a
regulatory sequence, such as an enhancer or a silencer, and a promoter. Insulators …

Chromatin remodeling complexes (CRCs) use ATP hydrolysis to maintain correct
expression profiles, chromatin stability, and inherited epigenetic states. More than 20 CRCs …

Chromatin insulators are genetic elements implicated in the organization of chromatin and
the regulation of transcription. In Drosophila, different insulator types were characterized by …

3 Suckow, J. et al.(1996) Genetic studies of the Lac repressor XV: 4000 single amino acid
substitutions and analysis of the resulting phenotypes on the basis of the protein structure. J …

▪ Abstract Chromatin boundaries and insulators are transcriptional regulatory elements that
modulate interactions between enhancers and promoters and protect genes from silencing …

Insulator elements play a role in gene regulation that is potentially linked to nuclear
organization. Boundary element-associated factors (BEAFs) 32A and 32B associate with …

Genome organization can regulate gene expression and promote cell fate transitions. The
differentiation of germline stem cells (GSCs) to oocytes in Drosophila involves changes in …

The MOF (males absent on the first)-containing NSL (non-specific lethal) complex binds to a
subset of active promoters in Drosophila melanogaster and is thought to contribute to proper …

Chromatin insulators are DNA–protein complexes with broad functions in nuclear biology.
Based on the ability of insulator proteins to interact with each other, it was originally found …