Clinical relevance of cross-reactivity in food allergy

AL Cox, PA Eigenmann, SH Sicherer - The Journal of Allergy and Clinical …, 2021 - Elsevier
The diagnosis and management of food allergy is complicated by an abundance of
homologous, cross-reactive proteins in edible foods and aeroallergens. This results in …

Clinical implications of cross-reactive food allergens

SH Sicherer - Journal of Allergy and Clinical Immunology, 2001 - Elsevier
As a consequence of the general increase in allergic sensitization, the prevalence of
hypersensitivity reactions to multiple foods that share homologous proteins has become a …

Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel

NSE Panel - Journal of Allergy and Clinical Immunology, 2010 - Elsevier
Food allergy is an important public health problem that affects children and adults and may
be increasing in prevalence. Despite the risk of severe allergic reactions and even death …

Fish allergens at a glance: variable allergenicity of parvalbumins, the major fish allergens

A Kuehn, I Swoboda, K Arumugam, C Hilger… - Frontiers in …, 2014 - frontiersin.org
Fish is a common trigger of severe, food-allergic reactions. Only a limited number of proteins
induce specific IgE-mediated immune reactions. The major fish allergens are the …

Identification of enolases and aldolases as important fish allergens in cod, salmon and tuna: component resolved diagnosis using parvalbumin and the new allergens

A Kuehn, C Hilger, C Lehners‐Weber… - Clinical & …, 2013 - Wiley Online Library
Background The majority of fish‐allergic patients are sensitized to parvalbumin, known to be
the cause of important IgE cross‐reactivity among fish species. Little is known about the …

Recombinant carp parvalbumin, the major cross-reactive fish allergen: a tool for diagnosis and therapy of fish allergy

I Swoboda, A Bugajska-Schretter, P Verdino… - The Journal of …, 2002 - journals.aai.org
IgE-mediated reactions to fish allergens represent one of the most frequent causes of food
allergy. We have constructed an expression cDNA library from carp (Cyprinus carpio) …

Allergy to fish parvalbumins: studies on the cross-reactivity of allergens from 9 commonly consumed fish

T Van Do, S Elsayed, E Florvaag, I Hordvik… - Journal of Allergy and …, 2005 - Elsevier
BACKGROUND: Fish-hypersensitive patients can probably tolerate some fish species while
being allergic to others. OBJECTIVE: To determine the allergenic cross-reactivity between 9 …

Fish hypersensitivity: I. In vitro and oral challenge results in fish-allergic patients

J Bernhisel-Broadbent, SM Scanlon… - Journal of Allergy and …, 1992 - Elsevier
The purpose of this study was to determine whether patients allergic to one fish species can
safely eat other fish species. Eleven atopic, food-allergic children and young adults with …

Parvalbumin, a cross-reactive fish allergen, contains IgE-binding epitopes sensitive to periodate treatment and Ca2+ depletion

A Bugajska-Schretter, L Elfman, T Fuchs… - Journal of Allergy and …, 1998 - Elsevier
Background: Type I allergy to fish is a severe health problem in countries in which a large
percentage of the population derive income from fishing. Objective: The aim of the study was …

Purification, biochemical, and immunological characterisation of a major food allergen: different immunoglobulin E recognition of the apo-and calcium-bound forms of …

A Bugajska-Schretter, M Grote, L Vangelista, P Valent… - Gut, 2000 - gut.bmj.com
BACKGROUND Almost 4% of the population suffer from food allergy which is an adverse
reaction to food with an underlying immunological mechanism. AIMS To characterise one of …