Limonoids: overview of significant bioactive triterpenes distributed in plants kingdom

A Roy, S Saraf - Biological and Pharmaceutical Bulletin, 2006 - jstage.jst.go.jp
The search for limonoids started long back when scientists started looking for the factor
responsible for bitterness in citrus which has negative impact on citrus fruit and juice industry …

Bioactive compounds: historical perspectives, opportunities, and challenges

BS Patil, GK Jayaprakasha… - Journal of agricultural …, 2009 - ACS Publications
Mom's conventional wisdom of eating fruits and vegetables to lead a healthy life has evolved
with scientific, fact-finding research during the past four decades due to advances in science …

In silico ADMET and molecular docking study on searching potential inhibitors from limonoids and triterpenoids for COVID-19

S Vardhan, SK Sahoo - Computers in biology and medicine, 2020 - Elsevier
Virtual screening of phytochemicals was performed through molecular docking, simulations,
in silico ADMET and drug-likeness prediction to identify the potential hits that can inhibit the …

Complex scaffold remodeling in plant triterpene biosynthesis

R De La Peña, H Hodgson, JCT Liu, MJ Stephenson… - Science, 2023 - science.org
Triterpenes with complex scaffold modifications are widespread in the plant kingdom.
Limonoids are an exemplary family that are responsible for the bitter taste in citrus (eg …

Limonin: a review of its pharmacology, toxicity, and pharmacokinetics

S Fan, C Zhang, T Luo, J Wang, Y Tang, Z Chen, L Yu - Molecules, 2019 - mdpi.com
Limonin is a natural tetracyclic triterpenoid compound, which widely exists in Euodia
rutaecarpa (Juss.) Benth., Phellodendron chinense Schneid., and Coptis chinensis Franch …

[HTML][HTML] Limonoids from Citrus: Chemistry, anti-tumor potential, and other bioactivities

YS Shi, Y Zhang, HT Li, CH Wu, HR El-Seedi… - Journal of Functional …, 2020 - Elsevier
Citrus limonoids are tetranortriterpenoids compounds mainly found in oranges, lemons,
grapefruits, and other fruits of Citrus. They are proved to be the leading cause of bitterness in …

Citrus limonoids: analysis, bioactivity, and biomedical prospects

GD Manners - Journal of Agricultural and Food Chemistry, 2007 - ACS Publications
Limonoids are a prominent group of secondary metabolites in citrus fruit. The bitter character
of some compounds in this group has historically compromised the quality of citrus fruit and …

Vitamin C and the role of citrus juices as functional food

N Martí, P Mena, JA Cánovas… - Natural product …, 2009 - journals.sagepub.com
The literature on the content and stability of vitamin C (ascorbic acid, AA) in citrus juices in
relation to industrial practices is reviewed. The role of vitamin C from citrus juices in human …

Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions

S Fan, Y Yan, Y Xia, Z Zhou, L Luo, M Zhu… - Nature …, 2023 - nature.com
Citrus fruit has long been considered a healthy food, but its role and detailed mechanism in
lifespan extension are not clear. Here, by using the nematode C. elegans, we identified that …

Interaction of selected terpenoids with two SARS-CoV-2 key therapeutic targets: An in silico study through molecular docking and dynamics simulations

SV Giofrè, E Napoli, N Iraci, A Speciale… - Computers in Biology …, 2021 - Elsevier
The outbreak of COVID-19 disease caused by SARS-CoV-2, along with the lack of targeted
medicaments, forced the scientific world to search for new antiviral formulations. In the …