Epithelial stem cells serve critical physiological functions in the generation, maintenance
and repair of diverse tissues through their ability to self-renew and spawn more specialized …

Epithelial mesenchymal transition (EMT) and mesenchymal epithelial transition (MET) are
genetic determinants of cellular plasticity. These programs operate in physiological …

Epithelial–mesenchymal transition (EMT) is a developmental cellular process occurring
during early embryo development, including gastrulation and neural crest cell migration. It …

It has been proposed that epithelial–mesenchymal transition (EMT) in mammary epithelial
cells and breast cancer cells generates stem cell features, and that the presence of EMT …

The transcription factor Snai2, encoded by the SNAI2 gene, is an evolutionarily conserved
C2H2 zinc finger protein that orchestrates biological processes critical to tissue development …

The epithelial to mesenchymal transition (EMT) is a fundamental developmental process
essential for normal embryonic development. It is also important during various pathogenic …

Epithelial-mesenchymal plasticity (EMP) refers to the ability of cells to dynamically
interconvert between epithelial (E) and mesenchymal (M) phenotypes, thus generating an …

Background Morphogenesis results from the coordination of distinct cell signaling pathways
controlling migration, differentiation, apoptosis, and proliferation, along stem/progenitor cell …

Aging of hematopoietic stem cells (HSCs) directly contributes to dysfunction of
hematopoietic and immune systems due to aging-associated alterations in HSC features …

Activation of the p16Ink4a-associated senescence pathway during aging breaks muscle
homeostasis and causes degenerative muscle disease by irreversibly dampening satellite …