Causal atlas between inflammatory bowel disease and mental disorders: a bi-directional 2-sample Mendelian randomization study

X Yang, L Yang, T Zhang, H Zhang, H Chen… - Frontiers in …, 2023 - frontiersin.org
Background The brain-gut axis link has attracted increasing attention, with observational
studies suggesting that the relationship between common mental disorders and …

Micronutrients, Vitamin D, and Inflammatory Biomarkers in COVID-19: A Systematic Review and Meta-analysis of Causal Inference Studies

Á Alcalá-Santiago, M Rodriguez-Barranco… - Nutrition …, 2024 - academic.oup.com
Context Experimental and observational studies suggest that circulating micronutrients,
including vitamin D (VD), may increase COVID-19 risk and its associated outcomes …

A systematic review and meta-analysis of the relationship between magnesium levels and malaria severity

KU Kotepui, A Mahittikorn, P Wilairatana… - Scientific Reports, 2024 - nature.com
Magnesium is associated with Plasmodium infections and malaria severity. This systematic
review and meta-analysis was conducted to synthesize the link between Plasmodium …

Causality of genetically determined metabolites on susceptibility to prevalent urological cancers: a two-sample Mendelian randomization study and meta-analysis

X Dai, H Wang, R Zhong, J Li, Y Hou - Frontiers in Genetics, 2024 - frontiersin.org
Background Prevalent urological cancers, including kidney, prostate, bladder, and testicular
cancers, contribute significantly to global cancer incidence and mortality. Metabolomics …

Inferring the genetic effects of serum homocysteine and vitamin B levels on autism spectral disorder through Mendelian randomization

T Jin, W Huang, Q Pang, Z He, L Yuan, H Zhang… - European Journal of …, 2024 - Springer
Purpose The previous studies have suggested that serum homocysteine (Hcy) and vitamin B
levels are potentially related to autism spectrum disorder (ASD). However, the causality …

Assessing the causal effect of genetically predicted metabolites and metabolic pathways on stroke

T Zhang, Y Cao, J Zhao, J Yao, G Liu - Journal of Translational Medicine, 2023 - Springer
Background Stroke is a common neurological disorder that disproportionately affects middle-
aged and elderly individuals, leading to significant disability and mortality. Recently, human …

Anorexia and bulimia in relation to ulcerative colitis: a Mendelian randomization study

Q Su, J Li, Y Lu, M Wu, J Liang, Z An - Frontiers in Nutrition, 2024 - frontiersin.org
Background Evidence for anorexia and bulimia in relation to the risk of ulcerative colitis (UC)
is limited and inconsistent. The objective of this research was to utilize bi-directional, two …

Circulating micronutrient levels and their association with sepsis susceptibility and severity: a Mendelian randomization study

Z Wei, Y Liu, X Mei, J Zhong, F Huang - Frontiers in Genetics, 2024 - frontiersin.org
Background: Sepsis, a global health challenge, necessitates a nuanced understanding of
modifiable factors for effective prevention and intervention. The role of trace micronutrients in …

Causal relationships between dyslexia and the risk of eight dementias

P Zhu, S Gao, S Wu, X Li, C Huang, Y Chen… - Translational …, 2024 - nature.com
Observational and genetic studies have reported the relationship between dyslexia and
Alzheimer's disease (AD). Until now, the causal effect of dyslexia on AD risk has remained …

Unraveling the causal pathways of maternal smoking and breastfeeding in the development of neuropsychiatric disorders: A Mendelian randomization perspective

Z Zhang, J Yu, Q Li, Y Zhao, L Tang, Y Peng… - Journal of Affective …, 2024 - Elsevier
Background Maternal smoking around birth (MSAB) and early-life breastfeeding (BAB)
represent critical factors that may exert enduring effects on neuropsychiatric health. Although …