Recent advances and prospects in gemcitabine drug delivery systems

S Paroha, J Verma, RD Dubey, RP Dewangan… - International Journal of …, 2021 - Elsevier
Cancer is a community health hazard which progress at a fatal rate in various countries
across the globe. An agent used for chemotherapy should exhibit ideal properties to be an …

[HTML][HTML] Solid lipid nanoparticles: An effective lipid-based technology for cancer treatment

M Akanda, MDSH Mithu, D Douroumis - Journal of Drug Delivery Science …, 2023 - Elsevier
Solid lipid nanoparticles (SLN) are considered at the forefront of nanotechnology's rapidly
developing field, with several potential applications in drug delivery and research. SLN …

High‐Load Gemcitabine Inorganic–Organic Hybrid Nanoparticles as an Image‐Guided Tumor‐Selective Drug‐Delivery System to Treat Pancreatic Cancer

M Ischyropoulou, K Sabljo, L Schneider… - Advanced …, 2023 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) has a devastating prognosis without effective
treatment options. Thus, there is an urgent need for more effective and safe therapies. Here …

Quercetin loaded cationic solid lipid nanoparticles in a mucoadhesive in situ gel—a novel intravesical therapy tackling bladder cancer

S Shawky, S Makled, A Awaad, N Boraie - Pharmaceutics, 2022 - mdpi.com
The study aim was to develop an intravesical delivery system of quercetin for bladder cancer
management in order to improve drug efficacy, attain a controlled release profile and extend …

Construction of tellurium-doped mesoporous bioactive glass nanoparticles for bone cancer therapy by promoting ROS-mediated apoptosis and antibacterial activity

Y Zhang, M Hu, W Zhang, X Zhang - Journal of Colloid and Interface …, 2022 - Elsevier
The commonly used treatment methods for bone cancer include chemotherapy, surgery and
radiotherapy, but there are disadvantages such as nonspecific distribution, high toxicity of …

Chitooligosaccharides inhibit tumor progression and induce autophagy through the activation of the p53/mTOR pathway in osteosarcoma

Z Pan, D Cheng, X Wei, S Li, H Guo, Q Yang - Carbohydrate Polymers, 2021 - Elsevier
Osteosarcoma is the most common primary sarcoma of bone. The use of
Chitooligosaccharide (COS) as a drug carrier is an emerging new strategy for cancer …

Advances in Pancreatic Cancer treatment by Nano-Based drug delivery systems

C Viegas, AB Patrício, J Prata, L Fonseca, AS Macedo… - Pharmaceutics, 2023 - mdpi.com
Pancreatic cancer represents one of the most lethal cancer types worldwide, with a 5-year
survival rate of less than 5%. Due to the inability to diagnose it promptly and the lack of …

Nanocarriers targeting the diseases of the pancreas

N Demirtürk, E Bilensoy - European Journal of Pharmaceutics and …, 2022 - Elsevier
Diseases of the pancreas include acute and chronic pancreatitis, exocrine pancreatic
insufficiency, diabetes and pancreatic cancer. These pathologies can be difficult to treat due …

[HTML][HTML] Recent advancements in the targeted delivery of Gemcitabine: Harnessing Nanomedicine for Enhanced Cancer Therapy

M Pourmadadi, A Aslani, D Hassan, A Sani, A Rahdar… - OpenNano, 2023 - Elsevier
Gemcitabine (GEM) is a chemotherapeutic drug widely used for treating pancreatic cancer
and other cancers. Despite its efficacy, GEM is associated with adverse side effects and …

Chemotherapy assessment in advanced multicellular 3D models of pancreatic cancer: Unravelling the importance of spatiotemporal mimicry of the tumor …

P Gupta, C Bermejo‐Rodriguez, H Kocher… - Advanced …, 2024 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is a challenge for global health with very low
survival rate and high therapeutic resistance. Hence, advanced preclinical models for …