Advanced strategies in high-throughput droplet screening for enzyme engineering

W Yan, X Li, D Zhao, M Xie, T Li, L Qian, C Ye… - Biosensors and …, 2023 - Elsevier
Enzymes, as biocatalysts, play a cumulatively important role in environmental purification
and industrial production of chemicals and pharmaceuticals. However, natural enzymes are …

Engineered stem cells by emerging biomedical stratagems

J Wang, X Zhang, H Chen, H Ren, M Zhou, Y Zhao - Science Bulletin, 2023 - Elsevier
Stem cell therapy holds immense potential as a viable treatment for a widespread range of
intractable disorders. As the safety of stem cell transplantation having been demonstrated in …

生物设施平台及其工业应用

赵国淼, 杨鑫, 张媛, 王靖, 谭剑, 魏超, 周娜娜… - 合成生物学, 2023 - synbioj.cip.com.cn
传统菌株改造和筛选实验存在操作烦琐, 耗时, 易错, 难以规模化等问题, 生物设施平台将自动化,
机器人技术, 数据分析与生物研究相结合, 通过导轨和机械手臂实现自动化操作 …

High-throughput screening of microbial strains in large-scale microfluidic droplets

Z Zhang, Q Guo, Y Wang, H Huang - Frontiers in Bioengineering and …, 2023 - frontiersin.org
The transformation of engineered microbial cells is a pivotal link in green biomanufacturing.
Its distinctive research application involves genetic modification of microbial chassis to …

Spontaneous charging-induced droplets directional steering

S Zhang, M Chi, T Liu, B Luo, C Cai, J Wang, Y Liu… - Nano Energy, 2024 - Elsevier
Droplet sorting is crucial for biochemical applications involving biomedicine, chemical
reactions, and material synthesis. Owing to its advantages of high precision and low sample …

Automation of 3D digital rolling circle amplification using a 3D-printed liquid handler

S Shin, HG Yun, H Chung, H Cho, S Choi - Biosensors and Bioelectronics, 2024 - Elsevier
Automation of liquid handling is indispensable to improve throughput and reproducibility in
biochemical assays. However, the incorporation of automated systems into laboratory …

Biofoundry and its industrial application

G ZHAO, X YANG, Y ZHANG, J WANG… - Synthetic Biology …, 2023 - synbioj.cip.com.cn
Traditional methods for strain isolation and improvement can be cumbersome, time-
consuming, error-prone, and difficult to scale up, leading to inefficiencies in research and …

Building an Arduino-Based Open-Source Programmable Multichannel Syringe Pump: A Useful Tool for Fluid Delivery in Microfluidics and Flow Chemistry

Y Wu, Y Chen, Y Cheng - Journal of Chemical Education, 2024 - ACS Publications
Microfluidics has attracted widespread interest in the fields of chemicals, materials,
pharmaceuticals, biology, etc. Integrating low-cost automation based on open-source …

One-step detection of multi-pollutants with different sizes in water by using cellulose-based composites

J Wang, M Zhang, Y Yang, G Dai, Q Pan, Y Kong… - Cellulose, 2024 - Springer
The contamination of multi-pollutants in source water, eg, bacterial and organic pollutants,
has been a long-term problem that influences our daily lives and industries. Despite great …

Recent advances in droplet sequential monitoring methods for droplet sorting

Y He, Y Qiao, L Ding, T Cheng, J Tu - Biomicrofluidics, 2023 - pubs.aip.org
Droplet microfluidics is an attractive technology to run parallel experiments with high
throughput and scalability while maintaining the heterogeneous features of individual …