Human inborn errors of immunity (IEI) are a group of 485 distinct genetic disorders affecting
children and adults. Signs and symptoms of IEI are heterogeneous, and accurate diagnosis …

The COVID-19 pandemic has transformed vaccinology. Rapid deployment of mRNA
vaccines has saved countless lives. However, these platforms have inherent limitations …

Despite co-evolving with humans for centuries and being intensely studied for decades, the
immune correlates of protection against Mycobacterium tuberculosis (Mtb) have yet to be …

Currently, there is only one licensed vaccine against tuberculosis (TB), the Bacillus Calmette–
Guérin (BCG). Despite its protective efficacy against TB in children, BCG has failed to protect …

Abstract The analysis of Adverse Events Following Immunization (AEFI) is important in a
balanced epidemiological evaluation of vaccines and in the issues related to vaccine injury …

Immune compromised children are threatened by a higher risk of infections; some of these
are preventable by vaccination. Primary care physicians play a fundamental role in …

The reported frequency and types of adverse events following initial vaccination and
revaccination with Bacille Calmette-Guérin (BCG) varies worldwide. Using active …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
the coronavirus disease 2019 (COVID-19), and its variants have brought unprecedented …

Purpose Activated phosphoinositide 3-kinase δ syndrome (APDS) is a primary
immunodeficiency first described in 2013, which is caused by gain-of-function mutations in …

Précis• In this meta-analysis of randomized controlled trials, we found that early-life bacillus
Calmette-Guérin–Denmark vaccination leads to an 11% reduction in the risk of eczema in …