Pyoderma gangrenosum: a review of pathogenesis and treatment

C Ahn, D Negus, W Huang - Expert review of clinical immunology, 2018 - Taylor & Francis
Introduction: Pyoderma gangrenosum (PG) is a complex neutrophilic dermatosis that can
occur as an idiopathic disease, in association with systemic conditions such as inflammatory …

Ustekinumab for extra-intestinal manifestations of inflammatory bowel disease: a systematic literature review

L Guillo, F D'amico, S Danese… - Journal of Crohn's and …, 2021 - academic.oup.com
Abstract Background and Aims Extra-intestinal manifestations [EIMs] are frequent in patients
with inflammatory bowel diseases [IBD] and are challenging conditions to manage. Tumour …

Surgical treatment of pyoderma gangrenosum with negative pressure wound therapy and skin grafting, including xenografts: personal experience and comprehensive …

K Eisendle, T Thuile, J Deluca, M Pichler - Advances in wound care, 2020 - liebertpub.com
Significance: Pyoderma gangrenosum (PG) is a rare debilitating autoinflammatory ulcerative
skin disease. No gold standard has been established for the treatment of PG. The role of …

Pyoderma gangrenosum and interleukin inhibitors: a semi-systematic review

H Ben Abdallah, K Fogh, C Vestergaard, R Bech - Dermatology, 2022 - karger.com
Background: Pyoderma gangrenosum (PG) is a rare ulcerating skin disease associated with
multiple comorbidities and increased mortality. In recent decades, newer biologics such as …

Biologic and small-molecule medications in the management of pyoderma gangrenosum

F McKenzie, D Cash, A Gupta… - Journal of …, 2019 - Taylor & Francis
Pyoderma gangrenosum (PG) is an uncommon inflammatory skin disorder characterized by
neutrophil dysfunction. There are currently no FDA-approved drugs for the treatment of this …

Ustekinumab as adjuvant treatment for all pyoderma gangrenosum subtypes

JS Westerdahl, KB Nusbaum, CG Chung… - Journal of …, 2022 - Taylor & Francis
Pyoderma gangrenosum (PG) is a rare neutrophilic skin disease characterized by painful
skin ulcerations with violaceous borders, although pustular, bullous, and vegetative clinical …

[HTML][HTML] Pyoderma gangrenosum induced by secukinumab in a patient with psoriasis successfully treated with ustekinumab

AJ Petty, MJ Whitley, A Balaban, K Ellington… - JAAD case …, 2020 - Elsevier
Pyoderma gangrenosum is an inflammatory condition characterized by the presence of
painful and necrotic ulcerations with a neutrophil-rich infiltrate. Although its pathogenesis is …

[HTML][HTML] Pyoderma gangrenosum following anti-TNF therapy in chronic recurrent multifocal osteomyelitis: drug reaction or cutaneous manifestation of the disease? A …

M Romagnuolo, C Moltrasio, C Iannone… - Frontiers in …, 2023 - frontiersin.org
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare autoinflammatory disease,
clinically characterized by chronic and recurrent episodes of osteoarticular inflammation …

[HTML][HTML] The Pathophysiology and Treatment of Pyoderma Gangrenosum—Current Options and New Perspectives

M Łyko, A Ryguła, M Kowalski, J Karska… - International Journal of …, 2024 - mdpi.com
Pyoderma gangrenosum (PG) is an uncommon inflammatory dermatological disorder
characterized by painful ulcers that quickly spread peripherally. The pathophysiology of PG …

The safety of treatments used in pyoderma gangrenosum

SR Feldman, FA Lacy, WW Huang - Expert Opinion on Drug Safety, 2018 - Taylor & Francis
Introduction: Pyoderma gangrenosum (PG) is a severe ulcerating orphan dermatosis
characterized by painful and rapidly progressive skin ulcers often associated with underlying …