Synthetic rubbers fabricated from 1, 3-butadiene (BD) and its substituted monomers have
been extensively used in tires, toughened plastics, and many other products owing to the …

A systematic study of the N-substitution reactions of 3-substituted pyrazoles under basic
conditions has been undertaken. Regioselective N1-alkylation,-arylation, and …

A rapidly developing approach adding new dimensions to acetylene chemistry relying on
employment of high basicity media such as alkali metal hydroxide suspensions in dimethyl …

Highly regioselective synthetic methodology leading to densely functionalised C (3), C (4)
and C (5) substituted pyrazoles 10a–q, 14a‐i and 16a–g via thermal [3+ 2]‐dipolar …

A mechanism for the synthesis of divinyl sulfide via nucleophilic addition of the hydrogen
sulfide anion to acetylene in the MOH (M= Na, K)/DMSO superbasic media has been studied …

A reaction of alk-4-ynals with aliphatic amino alcohols or 2-aminoethanethiol in the system
DMSO—KOH gives bicyclic N, O-and N, S-enaminals: 6-methylidenehexahydro-2 H-pyrrolo …

The previously described one-pot hydrative trimerization of acetylene to give 2-vinyloxy-1, 3-
butadiene in the KOH/DMSO superbase system has been studied using the MP2/6-311++ …

Immunoglobulins (Ig), which are an integral part of the immune system in humans and
animals, continue to surprise people with their effectiveness and importance every day since …

Aim: Disulfide bonds have critical functions in immunoglobulins (Ig), both in the J chain and
in the intermonomeric domain. Disulfide bonds can interact quite easily with hydroxyl ions. In …

No presente trabalho foram desenvolvidas novas e eficientes metodologias envolvendo
reações de ciclização para a obtenção de heterociclos sob diferentes condições reacionais …