Genetic association studies of ACE and PAI-1 genes in women with recurrent pregnancy loss

MT Su, SH Lin, YC Chen, PL Kuo - Thrombosis and …, 2013 - thieme-connect.com
A fine balance between coagulation and fibrinolysis is critical in early pregnancy.
Plasminogen activator inhibitor-1 (PAI-1) and angiotensin converting enzyme (ACE) are …

The G protein-coupled receptors: pharmacogenetics and disease

MD Thompson, WMI Burnham… - Critical reviews in clinical …, 2005 - Taylor & Francis
Genetic variation in G-protein coupled receptors (GPCRs) is associated with a wide
spectrum of disease phenotypes and predispositions that are of special significance …

The genetics of venous thromboembolism

R Gohil, G Peck, P Sharma - Thrombosis and haemostasis, 2009 - thieme-connect.com
We conducted a systematic and comprehensive meta-analysis on all candidate genes to
assess their genetic contribution to the aetiology of venous thromboembolism …

Low-molecular-weight heparin lowers the recurrence rate of preeclampsia and restores the physiological vascular changes in angiotensin-converting enzyme DD …

G Mello, E Parretti, C Fatini, C Riviello, F Gensini… - …, 2005 - Am Heart Assoc
Data from literature report that angiotensin-converting enzyme (ACE) insertion/deletion (I/D)
polymorphism affects the recurrence of preeclampsia and that low-molecular-weight heparin …

A prospective case–control study analyzes 12 thrombophilic gene mutations in Turkish couples with recurrent pregnancy loss

GI Yenicesu, M Cetin, O Ozdemir… - American journal of …, 2010 - Wiley Online Library
Citation Yenicesu GI, Cetin M, Ozdemir O, Cetin A, Ozen F, Yenicesu C, Yildiz C, Kocak N. A
prospective case–control study analyzes 12 thrombophilic gene mutations in Turkish …

Endothelial dysfunction in patients with spontaneous venous thromboembolism

R Migliacci, C Becattini, R Pesavento, G Davi… - …, 2007 - haematologica.org
Background and Objectives A high incidence of atherosclerotic lesions and cardiovascular
events has been reported in patients with spontaneous venous thromboembolism …

Recurrent pregnancy loss and its relation to combined parental thrombophilic gene mutations

O Ozdemir, GI Yenicesu, F Silan, B Köksal… - Genetic Testing and …, 2012 - liebertpub.com
Background and Aim: Recurrent pregnancy loss (RPL) is a heterogeneous disorder that has
been associated with antiphospholipid syndrome and other prothrombotic parameters. We …

G protein-coupled receptor (GPCR) pharmacogenomics

MD Thompson, D Reiner-Link, A Berghella… - Critical Reviews in …, 2024 - Taylor & Francis
The field of pharmacogenetics, the investigation of the influence of one or more sequence
variants on drug response phenotypes, is a special case of pharmacogenomics, a discipline …

Thrombophilic gene polymorphisms and recurrent pregnancy loss in Greek women

M Chatzidimitriou, D Chatzidimitriou… - International Journal …, 2017 - Wiley Online Library
Introduction Recurrent pregnancy loss (RPL) is a multifactorial disorder. The aim of this
study was the detection of various genetic polymorphisms and their correlation to RPL, in …

Atherosclerotic and thrombotic genetic and environmental determinants in Egyptian coronary artery disease patients: a pilot study

MS Fawzy, EA Toraih, NM Aly, A Fakhr-Eldeen… - BMC cardiovascular …, 2017 - Springer
Background Coronary artery disease (CAD) is the leading cause of morbidity and mortality
worldwide. Multiple genetic variants in combination with various environmental risk factors …