Structure-function of CD36 and importance of fatty acid signal transduction in fat metabolism

MY Pepino, O Kuda, D Samovski… - Annual review of …, 2014 - annualreviews.org
CD36 (cluster of differentiation 36) is a scavenger receptor that functions in high-affinity
tissue uptake of long-chain fatty acids (FAs) and contributes under excessive fat supply to …

The pathogenesis of obesity

SM Oussaada, KA Van Galen, MI Cooiman… - Metabolism, 2019 - Elsevier
Body fat mass increases when energy intake exceeds energy expenditure. In the long term,
a positive energy balance will result in obesity. The worldwide prevalence of obesity has …

Metabolic effects of non-nutritive sweeteners

MY Pepino - Physiology & behavior, 2015 - Elsevier
Until recently, the general belief was that non-nutritive sweeteners (NNSs) were healthy
sugar substitutes because they provide sweet taste without calories or glycemic effects …

[PDF][PDF] High dietary sugar reshapes sweet taste to promote feeding behavior in Drosophila melanogaster

CE May, A Vaziri, YQ Lin, O Grushko, M Khabiri… - Cell reports, 2019 - cell.com
Recent studies find that sugar tastes less intense to humans with obesity, but whether this
sensory change is a cause or a consequence of obesity is unclear. To tackle this question …

[HTML][HTML] Inflammation arising from obesity reduces taste bud abundance and inhibits renewal

A Kaufman, E Choo, A Koh, R Dando - PLoS biology, 2018 - journals.plos.org
Despite evidence that the ability to taste is weakened by obesity and can be rescued with
weight loss intervention, few studies have investigated the molecular effects of obesity on …

The development of sweet taste: From biology to hedonics

JA Mennella, NK Bobowski, DR Reed - Reviews in Endocrine and …, 2016 - Springer
From the age of 2 years, an American child is more likely to consume a sugar-sweetened
product than a fruit or vegetable on any given day—a troubling statistic, given that food …

Obesity-induced taste dysfunction, and its implications for dietary intake

F Harnischfeger, R Dando - International Journal of Obesity, 2021 - nature.com
The incidence of obesity has dramatically increased in recent years, and poses a public
health challenge for which an effective and scalable intervention strategy is yet to be found …

[HTML][HTML] The role of the Japanese traditional diet in healthy and sustainable dietary patterns around the world

AS Gabriel, K Ninomiya, H Uneyama - Nutrients, 2018 - mdpi.com
As incomes steadily increase globally, traditional diets have been displaced by diets that are
usually animal-based with a high content of “empty calories” or refined sugars, refined fats …

Systematic review of olfactory shifts related to obesity

M Peng, D Coutts, T Wang, YO Cakmak - Obesity reviews, 2019 - Wiley Online Library
Objective The modern food environment is a key driver of rising levels of obesity. While
olfaction is known to play a major role in food choice; however, its relationship to obesity is …

Genetics of taste and smell: poisons and pleasures

DR Reed, A Knaapila - Progress in molecular biology and translational …, 2010 - Elsevier
Eating is dangerous. While food contains nutrients and calories that animals need to
produce heat and energy, it may also contain harmful parasites, bacteria, or chemicals. To …