Natural killer cells: a promising immunotherapy for cancer
J Chu, F Gao, M Yan, S Zhao, Z Yan, B Shi… - Journal of translational …, 2022 - Springer
As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have
recently gained attention as an important type of innate immune regulatory cell. NK cells can …
recently gained attention as an important type of innate immune regulatory cell. NK cells can …
Uterine natural killer cells: functional distinctions and influence on pregnancy in humans and mice
Our understanding of development and function of natural killer (NK) cells has progressed
significantly in recent years. However, exactly how uterine NK (uNK) cells develop and …
significantly in recent years. However, exactly how uterine NK (uNK) cells develop and …
NK cell education via nonclassical MHC and non-MHC ligands
Y He, Z Tian - Cellular & molecular immunology, 2017 - nature.com
Natural killer (NK) cell education, a process for achieving functional maturation and self-
tolerance, has been previously defined by the interaction between self-major …
tolerance, has been previously defined by the interaction between self-major …
Clinical utility of natural killer cells in cancer therapy and transplantation
Natural killer (NK) cells recognize deranged cells that display stress receptors or loss of
major histocompatibility complex (MHC) class I. During development, NK cells become …
major histocompatibility complex (MHC) class I. During development, NK cells become …
SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer cells
C Viant, A Fenis, G Chicanne, B Payrastre… - Nature …, 2014 - nature.com
Natural killer (NK) cells are cytotoxic innate lymphoid cells that are involved in immune
defense. NK cell reactivity is controlled in part by MHC class I recognition by inhibitory …
defense. NK cell reactivity is controlled in part by MHC class I recognition by inhibitory …
Natural killer cells in inflammatory autoimmune diseases
Y Yang, J Day… - Clinical & …, 2021 - Wiley Online Library
Natural killer (NK) cells are a specialised population of innate lymphoid cells (ILCs) that help
control local immune responses. Through natural cytotoxicity, production of cytokines and …
control local immune responses. Through natural cytotoxicity, production of cytokines and …
Dynamic variability in SHP-1 abundance determines natural killer cell responsiveness
Z Wu, S Park, CM Lau, Y Zhong, S Sheppard… - Science …, 2021 - science.org
Interactions between human leukocyte antigen (HLA) molecules on target cells and the
inhibitory killer cell immunoglobulin-like receptors (KIRs) and heterodimeric inhibitory …
inhibitory killer cell immunoglobulin-like receptors (KIRs) and heterodimeric inhibitory …
NK cells: An attractive candidate for cancer therapy
B Valipour, K Velaei, A Abedelahi… - Journal of cellular …, 2019 - Wiley Online Library
Natural killer (NK) cells have significant capability in tumor immune‐surveillance. The ability
of lyse transformed cells immediately in an antigen‐independent manner make them an …
of lyse transformed cells immediately in an antigen‐independent manner make them an …
NK cells shape pancreatic and oral tumor microenvironments; role in inhibition of tumor growth and metastasis
We have recently shown that natural killer (NK) cells select and differentiate cancer stem
cells (CSCs)/undifferentiated tumors via secreted and membrane bound IFN-gamma (IFN-γ) …
cells (CSCs)/undifferentiated tumors via secreted and membrane bound IFN-gamma (IFN-γ) …
Education-dependent activation of glycolysis promotes the cytolytic potency of licensed human natural killer cells
JR Schafer, TC Salzillo, N Chakravarti… - Journal of Allergy and …, 2019 - Elsevier
Background The mechanism by which natural killer (NK) cell education results in licensed
NK cells with heightened effector function against missing self-targets is not known …
NK cells with heightened effector function against missing self-targets is not known …